4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

Base Information

Chemical Name:4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole
CAS No.:1103500-55-5
Molecular Formula:C₁₉H₂₂Cl₂N₂O₂
Molecular Weight:381.302
Hs Code.:

Synonyms:4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

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Chemical Property of 4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

Chemical Property:

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Technology Process of 4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

There total 1 articles about 4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1103500-50-0
4-[5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]azepane-1-carboxylic acid tert-butyl ester

: 1103500-55-5
4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 2 - 3h; Product distribution / selectivity;

Reference yield: 47.0%

: 1103500-71-5
6-bromobenzo[d]isothiazole-3-carboxylic acid methyl ester

: 1103500-55-5
4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

: 1103500-89-5
methyl 6-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)azepan-1-yl)benzo[d]isothiazole-3-carboxylate

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos; In xylene; at 130 ℃;

Reference yield:

: 1103500-55-5
4-((azepan-4-yloxy)methyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole

: 51934-41-9
4-iodobenzoic acid ethyl ester

: 1103500-83-9
4-{4-[5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]azepan-1-yl}benzoic acid ethyl ester

Guidance literature:: With copper(l) iodide; potassium carbonate; L-proline; In dimethyl sulfoxide; at 100 ℃; for 14h; Product distribution / selectivity;