(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

Base Information

Chemical Name:(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile
CAS No.:115662-71-0
Molecular Formula:C₂₄H₁₈ClNO₂
Molecular Weight:387.865
Hs Code.:

Synonyms:(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

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Technology Process of (E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

There total 2 articles about (E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 16616-42-5
p-chlorobenzoylphenylacetylene

: 104-47-2
p-methoxybenzylnitrile

: 115662-71-0
(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

: 115662-80-1
C₃₉H₂₇Cl₂NO₃

Guidance literature:: With sodium ethanolate; In benzene; at 100 ℃; for 0.166667h;
DOI:10.1055/s-1988-27546

Reference yield: 11.0%

: 16616-42-5
p-chlorobenzoylphenylacetylene

: 104-47-2
p-methoxybenzylnitrile

: 115662-71-0
(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

Guidance literature:: With sodium ethanolate; In diethyl ether; for 48h;
DOI:10.1055/s-1988-27546

Reference yield:

: 115662-71-0
(E)-5-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-5-oxo-3-phenyl-pent-2-enenitrile

: 115662-85-6
C₄₁H₂₉Cl₂NO₄

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / benzene / 48 h

With sodium methylate; In benzene;
DOI:10.1055/s-1988-27546