Technology Process of 1-diazo-3-ethyl-5-(m-methoxyphenyl)-3-methyl-2-pentanone
There total 6 articles about 1-diazo-3-ethyl-5-(m-methoxyphenyl)-3-methyl-2-pentanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 52 percent / lithium diisopropylamide, HMPA / tetrahydrofuran / Ambient temperature
2: 100 percent / hydrogen / 10percent palladium on carbon / methanol / 760 Torr
3: 5percent aq. sodium hydroxide / ethanol / 14 h / Heating
4: oxalyl chloride / benzene / 5 h / Ambient temperature
5: diethyl ether / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; oxalyl dichloride; hydrogen; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; benzene;
DOI:10.1021/ja00398a022
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 52 percent / lithium diisopropylamide, HMPA / tetrahydrofuran / Ambient temperature
2: 100 percent / hydrogen / 10percent palladium on carbon / methanol / 760 Torr
3: 5percent aq. sodium hydroxide / ethanol / 14 h / Heating
4: oxalyl chloride / benzene / 5 h / Ambient temperature
5: diethyl ether / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; oxalyl dichloride; hydrogen; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; benzene;
DOI:10.1021/ja00398a022
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / hydrogen / 10percent palladium on carbon / methanol / 760 Torr
2: 5percent aq. sodium hydroxide / ethanol / 14 h / Heating
3: oxalyl chloride / benzene / 5 h / Ambient temperature
4: diethyl ether / Ambient temperature
With
sodium hydroxide; oxalyl dichloride; hydrogen;
palladium on activated charcoal;
In
methanol; diethyl ether; ethanol; benzene;
DOI:10.1021/ja00398a022
