[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Base Information

Chemical Name:[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester
CAS No.:171336-39-3
Molecular Formula:C₃₇H₅₄O₁₃
Molecular Weight:706.828
Hs Code.:

[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Synonyms:[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Suppliers and Price of [1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

There total 11 articles about [1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 144358-24-7
<1S-<1α(4R*,5R*),3α,4β,5α,6α(2E,4R*,6R*),7β>>-1-<4-(acetyloxy)-5-methyl-3-methylene-6-phenylhexyl>4,6,7-trihydroxy-2,8-dioxabicyclo<3.2.1>octane-3,4,5-tricarboxylic acid, 6-(4,6-dimethyl-2-octenoate), 3,4,5-tris(1,1-dimethylethyl) ester

: 171336-39-3
[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Guidance literature:: With hydroxylamine hydrochloride; sodium acetate; In methanol; for 2.5h; Heating;
DOI:10.1021/jo961533m

Reference yield:

: 185201-25-6
(1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4-hydroxy-7-triethylsilanyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester

: 171336-39-3
[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / HF*pyridine / tetrahydrofuran / 6 h / 0 °C

2: 74 percent / TFA / CH₂Cl₂ / 11 h / Ambient temperature

3: 87 percent / CH₂Cl₂ / 1.) reflux 2 h, 2.) room temperature, 14 h, 3.) reflux 6 h

4: 97 percent / HONH₂*HCl, NaOAc*3H₂O / methanol / 2.5 h / Heating

With hydroxylamine hydrochloride; sodium acetate; pyridine hydrogenfluoride; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo961533m

Reference yield:

: 185201-24-5
(1S,3S,4S,5R,6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy)-4-hydroxy-1-((4S,5R)-4-hydroxy-5-methyl-3-methylene-6-phenyl-hexyl)-7-triethylsilanyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester

: 171336-39-3
[1S-(1α(4S,5R),3α,4β,5α,6α,7β)]-1-(4-acetyloxy-5-methyl-3-methylene-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3,4,5-tris(1,1-dimethylethyl) ester

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / Et₃N, DMAP / CH₂Cl₂ / 1 h / 0 °C

2: 87 percent / HF*pyridine / tetrahydrofuran / 6 h / 0 °C

3: 74 percent / TFA / CH₂Cl₂ / 11 h / Ambient temperature

4: 87 percent / CH₂Cl₂ / 1.) reflux 2 h, 2.) room temperature, 14 h, 3.) reflux 6 h

5: 97 percent / HONH₂*HCl, NaOAc*3H₂O / methanol / 2.5 h / Heating

With dmap; hydroxylamine hydrochloride; sodium acetate; pyridine hydrogenfluoride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo961533m