3,5-Dibromopicolinic acid

Base Information

• Chemical Name: 3,5-Dibromopicolinic acid
• CAS No.: 61830-40-8
• Molecular Formula: C₆H₃Br₂NO₂
• Molecular Weight: 280.903
• Hs Code.: 2933399090
• European Community (EC) Number: 838-560-0
• DSSTox Substance ID: DTXSID30494110
• Wikidata: Q72464955
• Mol file: 61830-40-8.mol

Synonyms:3,5-Dibromopicolinic acid;61830-40-8;3,5-Dibromopyridine-2-carboxylic acid;MFCD06411110;3,5-DibroMopicolinicacid;3,5-dibromo-2-pyridinecarboxylic acid;2-Pyridinecarboxylic acid, 3,5-dibromo-;SCHEMBL4976345;DTXSID30494110;BXFONYCBYSYAJE-UHFFFAOYSA-N;AKOS015835080;AB25162;DS-11866;SY102652;CS-0041189;FT-0647216;EN300-119551;W16708;A833438

Chemical Property of 3,5-Dibromopicolinic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 337.6 ºC at 760 mmHg
• Flash Point: 158ºC
• PSA: 50.19000
• Density: 2.202 g/cm³
• LogP: 2.30480
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 280.85100
• Heavy Atom Count: 11
• Complexity: 165

Purity/Quality:

99% ^*data from raw suppliers

3,5-DibromopicolinicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=NC(=C1Br)C(=O)O)Br

Technology Process of 3,5-Dibromopicolinic acid

There total 5 articles about 3,5-Dibromopicolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dibromo-2-cyanopyridine (61830-09-9) → 3,5-dibromopyridine-2-carboxylic acid (61830-40-8)

Guidance literature:

With sulfuric acid; acetic acid; In hexane; water;

Reference yield:

3,5-dibromo-4-chloro-pyridine-2-carboxylic acid (698393-07-6) → 3,5-dibromopyridine-2-carboxylic acid (61830-40-8)

Guidance literature:

With phosphorus; hydrogen iodide;

Reference yield:

3,5-dibromo-4-hydroxy-pyridine-2-carboxylic acid (858852-20-7,959244-23-6) → 3,5-dibromopyridine-2-carboxylic acid (61830-40-8)

Guidance literature:

Multi-step reaction with 3 steps

1: POCl₃; PCl₅ / Behandeln des Reaktionsprodukts mit Methanol

2: ethanolic KOH

3: aqueous HI; red phosphorus

With phosphorus; potassium hydroxide; phosphorus pentachloride; hydrogen iodide; trichlorophosphate;

upstream raw materials:

3,5-dibromo-4-chloro-pyridine-2-carboxylic acid

3,5-dibromo-4-hydroxy-pyridine-2-carboxylic acid

3,5-dibromo-4-chloro-pyridine-2-carboxylic acid methyl ester

3,5-dibromo-2-cyanopyridine

Downstream raw materials:

methyl 3,5-dibromopyridine-2-carboxylate

Refernces