2,3,7,8-TETRAMETHOXYDIBENZOFURAN

Base Information

• Chemical Name: 2,3,7,8-TETRAMETHOXYDIBENZOFURAN
• CAS No.: 109881-52-9
• Molecular Formula: C₁₆H₁₆O₅
• Molecular Weight: 288.3
• Hs Code.: 2932999099
• Mol file: 109881-52-9.mol

Synonyms:2,3,7,8-TETRAMETHOXYDIBENZOFURAN

Chemical Property of 2,3,7,8-TETRAMETHOXYDIBENZOFURAN

Chemical Property:

• Vapor Pressure: 1.29E-06mmHg at 25°C
• Boiling Point: 411.9 ºC at 760 mmHg
• Flash Point: 218.2 ºC
• PSA: 50.06000
• Density: 1.219 g/cm³
• LogP: 3.62040

Purity/Quality:

99% ^*data from raw suppliers

2,3,7,8-Tetramethoxydibenzo[b,d]furan 95+% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,7,8-TETRAMETHOXYDIBENZOFURAN

There total 5 articles about 2,3,7,8-TETRAMETHOXYDIBENZOFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

bis(3, 4-dimethoxyphenyl)ether (101432-12-6) → 2,3,7,8-tetramethoxydibenzofuran (76303-42-9,109881-52-9)

Guidance literature:

With molybdenum(V) chloride; titanium tetrachloride; In dichloromethane; at 0 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/ol403304t

Reference yield:

3,4-dimethoxyphenol (2033-89-8) + 1-iodo-3,4-dimethoxybenzene (5460-32-2) → 2,3,7,8-tetramethoxydibenzofuran (76303-42-9,109881-52-9)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide; N,N-dimethylglycine hydrochoride / 1,4-dioxane / 20 h / 110 °C / Inert atmosphere

2: titanium tetrachloride; molybdenum(V) chloride / dichloromethane / 0.33 h / 0 °C / Inert atmosphere

With copper(l) iodide; molybdenum(V) chloride; titanium tetrachloride; N,N-dimethylglycine hydrochoride; In 1,4-dioxane; dichloromethane;

DOI:10.1021/ol403304t

Reference yield:

3,6-dihydroxy-2,7-dimethoxydibenzofurane (72442-70-7) → 2,3,7,8-tetramethoxydibenzofuran (76303-42-9,109881-52-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / Heating

2: 0.29 g / potassium carbonate / acetone; methanol / 3 h / Heating

With pyridine; potassium carbonate; In methanol; acetone;

upstream raw materials:

2,8-diacetoxy-3,7-dimethoxy-dibenzofuran

dimethyl sulfoxide

3,6-dihydroxy-2,7-dimethoxydibenzofurane

bis(3, 4-dimethoxyphenyl)ether

Refernces

• 1、 Jurd, Leonard. "Quinones and Quinone Methides. VII. Reactions of 1,4-Naphthoquinone and 1,4-Benzoquinones with 4-Hydroxy-2H-1-benzopyran-2-one and 5,5-Dimethylcyclohexane-1,3-dione in Acid Solutions". . p. 1603 - 1610. Retrieved 2007/10/02.