2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE

Base Information

Chemical Name:2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE
CAS No.:906092-48-6
Molecular Formula:C₁₅H₁₂BrN₃O₃S
Molecular Weight:394.249
Hs Code.:
Mol file:906092-48-6.mol

Synonyms:2-bromo-1-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyriridin-4-yl]-ethanone

Suppliers and Price of 2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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American Custom Chemicals Corporation
2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO-[2,3-D]-PYRIMIDIN-4-YL)ETHANONE 95.00%
5MG
$ 504.58

Total 0 raw suppliers

Chemical Property of 2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE

Chemical Property:

Purity/Quality:: 2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO-[2,3-D]-PYRIMIDIN-4-YL)ETHANONE 95.00% ^*data from reagent suppliers

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Technology Process of 2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE

There total 2 articles about 2-BROMO-1-(7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.6%

: 906092-47-5
1-[7-(Toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-ethanone

: 906092-48-6
2-bromo-1-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyriridin-4-yl]-ethanone

Guidance literature:: 1-[7-(Toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-ethanone; With hydrogen bromide; bromine; In acetic acid; at 20 ℃; for 5h;

With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

: 479633-63-1
4-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine

: 906092-48-6
2-bromo-1-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyriridin-4-yl]-ethanone

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen iodide / water / 6 h / 0 - 20 °C

2: bis-triphenylphosphine-palladium(II) chloride / toluene / 8 h / 90 °C

3: hydrogenchloride; methanol; water / tetrahydrofuran / 4 h / 20 °C

4: hydrogen bromide; bromine; acetic acid / 5 h / 20 °C

With hydrogenchloride; methanol; water; hydrogen bromide; hydrogen iodide; bromine; acetic acid; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; toluene;

Reference yield: 72.0%

: 906092-48-6
2-bromo-1-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyriridin-4-yl]-ethanone

: 17356-08-0
thiourea

: 952521-69-6
4-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-thiazol-2-ylamine

Guidance literature:: 2-bromo-1-[7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyriridin-4-yl]-ethanone; thiourea; In acetone; at 20 ℃; for 4h;

With triethylamine; for 1h;