DL-VALINE-2-D1

Base Information

• Chemical Name: DL-VALINE-2-D1
• CAS No.: 14246-21-0
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 118.14
• Mol file: 14246-21-0.mol

Synonyms:DL-Valine-2-d;Valine-2-d, DL- (8CI);DL-(a-2H)Valine;

Chemical Property of DL-VALINE-2-D1

Chemical Property:

• Melting Point: 295 °C (subl.)(lit.)
• Boiling Point: 213.642 °C at 760 mmHg
• Flash Point: 83.008 °C
• PSA: 63.32000
• Density: 1.073 g/cm³
• LogP: 0.75460

Purity/Quality:

99% ^*data from raw suppliers

DL-Valine-2-d1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: DL-Valine-2-d1 (CAS# 14246-21-0) is a useful isotopically labeled research compound.

Technology Process of DL-VALINE-2-D1

There total 2 articles about DL-VALINE-2-D1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2--(2-2H)-3-methylbutyronitrile (139512-46-2) → D/L-(2-2H)valine (14246-21-0)

Guidance literature:

With hydrogenchloride; Yield given. Multistep reaction; 1) Et₂O, 12h, 2) 12h, reflux;

DOI:10.1016/S0040-4020(01)80725-0

Reference yield:

→ D/L-(2-2H)valine (14246-21-0)

Guidance literature:

DL-Valin, D2O/Acetanhydrid;

DOI:10.1002/cber.19711041131

Reference yield:

D/L-(2-2H)valine (14246-21-0) → D/L-(2-2H)-valine benzhydryl ester tosyl ammonium salt

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; H₂O

2: acetonitrile

In tetrahydrofuran; water; acetonitrile;

DOI:10.1016/S0040-4020(01)80725-0

upstream raw materials:

2--(2-2H)-3-methylbutyronitrile

Refernces

• 1、 Lackner. "Synthesis of selective deuterated pentapeptide lactones and specifically labeled in the or peptide ring actinomycins". . p. 3653 - 3678. Retrieved 2007/10/06.