Technology Process of C15H22O3
There total 8 articles about C15H22O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C15H20O2;
With
(1,4,7,10-tetraoxacyclododecane); Zeise's dimer;
In
1,2-dimethoxyethane;
at 40 ℃;
for 1.5h;
Glovebox;
With
water;
In
1,2-dimethoxyethane;
for 0.166667h;
Overall yield = 61 %; regioselective reaction;
Glovebox;
DOI:10.1016/j.tetlet.2012.07.010
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 1H-imidazole / dichloromethane / 1 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide / 0.67 h / -78 °C
2.2: 1 h / -78 °C
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
4.1: Zeise's dimer; (1,4,7,10-tetraoxacyclododecane) / 1,2-dimethoxyethane / 1.5 h / 40 °C / Glovebox
4.2: 0.17 h / Glovebox
With
1H-imidazole; n-butyllithium; (1,4,7,10-tetraoxacyclododecane); Zeise's dimer; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/j.tetlet.2012.07.010
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium tetrahydroborate / ethanol / 0 - 20 °C
2.1: 1H-imidazole / dichloromethane / 1 h / 20 °C
3.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide / 0.67 h / -78 °C
3.2: 1 h / -78 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
5.1: Zeise's dimer; (1,4,7,10-tetraoxacyclododecane) / 1,2-dimethoxyethane / 1.5 h / 40 °C / Glovebox
5.2: 0.17 h / Glovebox
With
1H-imidazole; sodium tetrahydroborate; n-butyllithium; (1,4,7,10-tetraoxacyclododecane); Zeise's dimer; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane; ethanol; dichloromethane;
DOI:10.1016/j.tetlet.2012.07.010
