BIS(2-METHOXYPHENYL)PHOSPHINE

Base Information

• Chemical Name: BIS(2-METHOXYPHENYL)PHOSPHINE
• CAS No.: 10177-79-4
• Molecular Formula: C14H15 O2 P
• Molecular Weight: 246.246
• Hs Code.: 2909309090
• Mol file: 10177-79-4.mol

Synonyms:Phosphine,bis(o-methoxyphenyl)- (7CI,8CI); Bis(2-methoxyphenyl)phosphine;Bis(o-anisyl)phosphine; Bis(o-methoxyphenyl)phosphine; Di-o-anisylphosphine

Chemical Property of BIS(2-METHOXYPHENYL)PHOSPHINE

Chemical Property:

• Melting Point: 86-90°C
• PSA: 32.05000
• LogP: 2.33310

Purity/Quality:

98% ^*data from raw suppliers

Bis(2-methoxyphenyl)phosphine 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reactant for:Allylation of phenolsSynthesis of neutral rhodium(I) complexesDinuclear Pd(II) complexes bearing bis-bidentate tetraphos ligandsCO-ethylene copolymerization reactionsSuzuki-Miyaura reaction for synthesis of alkyl derivatives phosphine sulfonate (P-O) ligands

Technology Process of BIS(2-METHOXYPHENYL)PHOSPHINE

There total 11 articles about BIS(2-METHOXYPHENYL)PHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tris(o-methoxyphenyl)phosphine (4731-65-1) → bis(2-methoxyphenyl)phosphine (10177-79-4)

Guidance literature:

With sodium; In tetrahydrofuran; ammonia; at -40 ℃; for 2h;

Reference yield: 88.0%

Bisphosphine oxide (71360-04-8) → bis(2-methoxyphenyl)phosphine (10177-79-4)

Guidance literature:

With 2-bromoanisole; trichlorosilane; triethylamine; phosphorus trichloride; In acetonitrile; at 20 - 70 ℃; for 2h; Large scale;

Reference yield: 45.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + tris(o-methoxyphenyl)phosphine (4731-65-1) → bis(2-methoxyphenyl)phosphine (10177-79-4) + 4-(2-Methoxy-phenylphosphanyl)-butan-1-ol

Guidance literature:

With lithium; In tetrahydrofuran; diethyl ether; for 16h; Ambient temperature;

upstream raw materials:

tetrahydrofuran

tris(o-methoxyphenyl)phosphine

benzyl-di(2-methoxyphenyl)phosphine

Bisphosphine oxide

Downstream raw materials:

(κ2-O,P-(bis(2-methoxyphenyl)phosphino)benzenesulfonate)bis(2-methoxyphenyl)phosphinecarbonylrhodium(I)

Refernces

• 1、 Andrews, Ryan J.,Elser, Iris,Stephan, Douglas W.. "9-BBN and chloride catalyzed reduction of chlorophosphines to phosphines and diphosphines". supporting information. p. 1740 - 1743. Retrieved 2022/02/17.
• 2、 Barrett, Adam N.,Woof, Callum R.,Goult, Christopher A.,Gasperini, Danila,Mahon, Mary F.,Webster, Ruth L.. "Hydrogen/Halogen Exchange of Phosphines for the Rapid Formation of Cyclopolyphosphines". supporting information. p. 16826 - 16833. Retrieved 2021/11/04.