4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine

Base Information

Chemical Name:4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine
CAS No.:143665-51-4
Molecular Formula:C₁₉H₂₆N₂O₂
Molecular Weight:314.428
Hs Code.:
DSSTox Substance ID:DTXSID801156541

Synonyms:SCHEMBL8790592;DTXSID801156541;4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine;143665-51-4

Suppliers and Price of 4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:314.199428076
Heavy Atom Count:23
Complexity:339

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)CCN(C)CC2=CC(=C(C=C2)OC)OC)N

Technology Process of 4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine

There total 6 articles about 4-Amino-N-[(3,4-dimethoxyphenyl)methyl]-N,3-dimethylbenzeneethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143665-37-6
2-(3-methyl-4-nitrophenyl)acetic acid

: 143665-51-4
4-{2-[(3,4-Dimethoxy-benzyl)-methyl-amino]-ethyl}-2-methyl-phenylamine

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 3 h / Heating

2: NaHCO₃ / acetone / 6 h / Ambient temperature

3: H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

4: LiAlH₄ / tetrahydrofuran / 3 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00013a017

Reference yield:

: 163981-95-1
(3-Methyl-4-nitro-phenyl)-acetyl chloride

: 143665-51-4
4-{2-[(3,4-Dimethoxy-benzyl)-methyl-amino]-ethyl}-2-methyl-phenylamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaHCO₃ / acetone / 6 h / Ambient temperature

2: H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

3: LiAlH₄ / tetrahydrofuran / 3 h / Heating

With lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00013a017

Reference yield:

: 206874-44-4
2-Diazo-1-(3-methyl-4-nitro-phenyl)-ethanone

: 143665-51-4
4-{2-[(3,4-Dimethoxy-benzyl)-methyl-amino]-ethyl}-2-methyl-phenylamine

Guidance literature:: Multi-step reaction with 5 steps

1: Ag₂O, aq. Na₂S₂O₃ / dioxane / 3 h / 75 - 80 °C

2: SOCl₂ / 3 h / Heating

3: NaHCO₃ / acetone / 6 h / Ambient temperature

4: H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

5: LiAlH₄ / tetrahydrofuran / 3 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; hydrogen; sodium hydrogencarbonate; sodium thiosulfate; silver(l) oxide; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; ethanol; acetone;
DOI:10.1021/jm00013a017