4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid

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Chemical Name:4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid
CAS No.:1222173-54-7
Molecular Formula:C₂₈H₂₃FN₄O₃
Molecular Weight:482.514
Hs Code.:

Synonyms:4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid

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Chemical Property of 4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid

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Technology Process of 4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid

There total 1 articles about 4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1222174-97-1
4-{[(5-bromo-1-methyl-1H-pyrazole-3-carbonyl)amino]methyl}benzoic acid

: 1222174-96-0
5-bromo-2-(4-fluoro-3-methyl-phenyl)-indole-1-carboxylic acid tert-butyl ester

: 1222173-54-7
4-[({5-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-5-yl]-1-methyl-1H-pyrazole-3-carbonyl}-amino)-methyl]-benzoic acid

Guidance literature:: 5-bromo-2-(4-fluoro-3-methyl-phenyl)-indole-1-carboxylic acid tert-butyl ester; With potassium acetate; bis(pinacol)diborane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; at 100 ℃; for 2h; Inert atmosphere;

4-{[(5-bromo-1-methyl-1H-pyrazole-3-carbonyl)amino]methyl}benzoic acid; With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; water; N,N-dimethyl-formamide; at 85 ℃; for 8h; Inert atmosphere;