ALPHA-CHLORO-2-NITROBENZALDOXIME

Base Information

• Chemical Name: ALPHA-CHLORO-2-NITROBENZALDOXIME
• CAS No.: 35447-75-7
• Molecular Formula: C7H5ClN2O3
• Molecular Weight: 200.581
• Hs Code.: 2925290090
• Mol file: 35447-75-7.mol

Synonyms:Benzoylchloride, o-nitro-, oxime (6CI);2-Nitrobenzohydroximoyl chloride;Benzenecarboximidoylchloride, N-hydroxy-2-nitro-;N-Hydroxy-2-nitrobenzenecarboximidoyl chloride;α-Chloro-2-nitrobenzaldoxime;

Chemical Property of ALPHA-CHLORO-2-NITROBENZALDOXIME

Chemical Property:

• Vapor Pressure: 2.26E-06mmHg at 25°C
• Refractive Index: 1.612
• Boiling Point: 377.6 °C at 760 mmHg
• Flash Point: 182.1 °C
• PSA: 78.41000
• Density: 1.5 g/cm³
• LogP: 2.49260

Purity/Quality:

97% ^*data from raw suppliers

α-Chloro-2-nitrobenzaldoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALPHA-CHLORO-2-NITROBENZALDOXIME

There total 4 articles about ALPHA-CHLORO-2-NITROBENZALDOXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

2-nitrobenzaldehyde oxime (3717-25-7,4836-00-4,6635-41-2) → N-hydroxy-2-nitrobenzimidoyl chloride (35447-75-7)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 20 ℃; for 14h;

Reference yield:

2-nitro-benzaldehyde (552-89-6) → N-hydroxy-2-nitrobenzimidoyl chloride (35447-75-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol; water; tetrahydrofuran

2: N-chloro-succinimide / N,N-dimethyl-formamide

With N-chloro-succinimide; hydroxylamine hydrochloride; sodium acetate; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;

DOI:10.1021/acs.orglett.5b02680

Reference yield:

→ N-hydroxy-2-nitrobenzimidoyl chloride (35447-75-7)

Guidance literature:

With chloroform; chlorine;

upstream raw materials:

(E)-2-nitrobenzaldehyde oxime

2-nitrobenzaldehyde oxime

2-nitro-benzaldehyde

Downstream raw materials:

N'-hydroxy-2-nitrobenzimidamide

3'-(2-nitro-phenyl)-4'H-spiro[adamantane-2,5'-isoxazole]

3-(2-nitrophenyl)-5-phenyl-1,2-oxazole

5-Ethoxy-6,6,7,7-tetramethyl-2-(2-nitro-phenyl)-4-oxa-1,3-diaza-bicyclo[3.2.0]hept-2-ene