3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole

Base Information

• Chemical Name: 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole
• CAS No.: 1086450-06-7
• Molecular Formula: C₂₈H₂₅NO₂S₂
• Molecular Weight: 471.644
• Mol file: 1086450-06-7.mol

Synonyms:3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole

Chemical Property of 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole

There total 1 articles about 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4,4,5,5-tetramethyl-2-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)-thiophen-2-yl)-1,3,2-dioxaborolane (1086450-04-5) + 3-bromo-2-phenyl-1H-indole (54006-72-3) → 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole (1086450-06-7)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; for 18h; Heating;

DOI:10.1016/j.tet.2008.08.045

Reference yield: 86.0%

3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole (1086450-06-7) + 2-iodo-9,9-dimethyl-9H-fluorene (144981-85-1) → 3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-1-(9,9-dimethylfluoren-2-yl)-2-phenylindole (1086450-08-9)

Guidance literature:

With 18-crown-6 ether; copper; potassium carbonate; In various solvent(s); for 36h; Heating;

DOI:10.1016/j.tet.2008.08.045

upstream raw materials:

4,4,5,5-tetramethyl-2-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)-thiophen-2-yl)-1,3,2-dioxaborolane

3-bromo-2-phenyl-1H-indole

Downstream raw materials:

3-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-1-(9,9-dimethylfluoren-2-yl)-2-phenylindole