4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine

Base Information

• Chemical Name: 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine
• CAS No.: 97817-23-7
• Molecular Formula: C6H9N3S
• Molecular Weight: 155.224
• Hs Code.: 2934999090
• European Community (EC) Number: 828-372-7
• DSSTox Substance ID: DTXSID50542824
• Wikidata: Q72506950
• Mol file: 97817-23-7.mol

Synonyms:97817-23-7;4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine;4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridin-2-amine;4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-amine;4,5,6,7-Tetrahydro-[1,3]thiazolo[5,4-c]pyridin-2-amine;MFCD06657759;4H,5H,6H,7H-[1,3]THIAZOLO[5,4-C]PYRIDIN-2-AMINE;4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridin-2-ylamine;4,5,6,7-tetrahydro-thiazolo(5,4-c)pyridin-2-ylamine;SCHEMBL172067;2-amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine;Thiazolo[5,4-c]pyridin-2-amine, 4,5,6,7-tetrahydro-;AMY7090;DTXSID50542824;YYZRTZLOUDOIGR-UHFFFAOYSA-N;AKOS000141194;AC-7184;CS-11074;SY004724;CS-0039283;EN300-37561;F19592;A858609;J-514057;4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridin-2-yl-amine;Thiazolo[5,4-c]pyridin-2-amine,4,5,6,7-tetrahydro-;Z234895083

Chemical Property of 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine

Chemical Property:

• Vapor Pressure: 3.65E-05mmHg at 25°C
• Melting Point: 195 °C
• Refractive Index: 1.644
• Boiling Point: 353.2 °C at 760 mmHg
• Flash Point: 167.4 °C
• PSA: 79.18000
• Density: 1.323 g/cm³
• LogP: 1.28100
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 155.05171847
• Heavy Atom Count: 10
• Complexity: 130

Purity/Quality:

97% ^*data from raw suppliers

4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCC2=C1N=C(S2)N

Technology Process of 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine

There total 6 articles about 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

VUF 9165 (124458-10-2) → 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (97817-23-7)

Guidance literature:

With formaldehyd; acetic acid; In methanol;

Reference yield: 87.0%

tert-butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate (365996-05-0) → 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (97817-23-7)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 3h;

Reference yield:

1-(2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-yl)ethan-1-one (124458-11-3) → 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (97817-23-7)

Guidance literature:

With sodium hydroxide; ammonium chloride; In ethanol; chloroform;

upstream raw materials:

thiourea

3-bromo-piperidin-4-one-hydrobromide

1-(2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-yl)ethan-1-one

VUF 9165

Downstream raw materials:

C₉H₁₁N₅S₂

tert-butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

2-phenoxycarbonylamino-6,7-dihydro-4H-thiazolo(5,4-c)pyridine-5-carboxylic acid tert-butyl ester

2-(3-methyl-ureido)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid tert-butyl ester