1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one

Base Information

• Chemical Name: 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one
• CAS No.: 1332607-96-1
• Molecular Formula: C₁₇H₁₂Cl₂N₂O
• Molecular Weight: 331.201
• Mol file: 1332607-96-1.mol

Synonyms:1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one

Chemical Property of 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one

There total 3 articles about 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

bis(trichloromethyl) carbonate (32315-10-9) + (E,E)-N,N′-bis(4-chlorophenyl)butane-2,3-diimine (19215-48-6) → 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one (1332607-96-1)

Guidance literature:

With triethylamine; In toluene; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1021/acs.joc.7b02344

Reference yield: 73.0%

(E)-3-(4-chlorophenylimino)butan-2-one (1332607-90-5) + p-chlorphenylisocyanate (104-12-1) → 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one (1332607-96-1)

Guidance literature:

(E)-3-(4-chlorophenylimino)butan-2-one; With lithium carbonate; triethylamine; In toluene; at 20 ℃; for 1.5h; Darkness; Inert atmosphere;

p-chlorphenylisocyanate; In toluene; at 20 ℃; for 24h; Inert atmosphere; Darkness;

DOI:10.1021/jo201335y

Reference yield:

4-chloro-aniline (106-47-8) → 1,3-bis(4-chlorophenyl)-4,5-dimethyleneimidazolidin-2-one (1332607-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / 12 h / 20 °C / Inert atmosphere

2.1: lithium carbonate; triethylamine / toluene / 1.5 h / 20 °C / Darkness; Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere; Darkness

With lithium carbonate; triethylamine; In methanol; toluene;

DOI:10.1021/jo201335y

upstream raw materials:

(E)-3-(4-chlorophenylimino)butan-2-one

p-chlorphenylisocyanate

4-chloro-aniline

bis(trichloromethyl) carbonate