4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

Base Information

Chemical Name:4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide
CAS No.:1198088-28-6
Molecular Formula:BrH*C₂₀H₁₈N₄O₂S
Molecular Weight:459.366
Hs Code.:

Synonyms:4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

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Chemical Property of 4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

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Technology Process of 4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

There total 4 articles about 4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 2114-02-5
amidinothiocarbamide

: 1198088-27-5
4-(2-bromoacetyl)phenyl 4-cyclopropylbenzoate

: 1198088-28-6
4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

Guidance literature:: In acetone; Reflux;

Reference yield:

: 1198088-26-4
4-acetylphenyl 4-cyclopropylbenzoate

: 1198088-28-6
4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / chloroform

2: acetone / Reflux

With bromine; In chloroform; acetone;

Reference yield:

: 1798-82-9
4-cyclopropylbenzoic acid

: 1198088-28-6
4-(2-guanidinothiazol-4-yl)phenyl 4-cyclopropylbenzoate hydrobromide

Guidance literature:: Multi-step reaction with 4 steps

1.1: oxalyl dichloride / dichloromethane

2.1: sodium hydride / dichloromethane; mineral oil / 0.17 h

2.2: 3 h

3.1: bromine / chloroform

4.1: acetone / Reflux

With oxalyl dichloride; bromine; sodium hydride; In dichloromethane; chloroform; acetone; mineral oil;