Chemical Property of 2-Oxo-2H-1-benzopyran-7-yl icosa-5,8,11,14-tetraenoate
Chemical Property:
- Boiling Point:584.7±50.0 °C(Predicted)
- Flash Point:14℃
- PSA：56.51000
- Density:1.052±0.06 g/cm3(Predicted)
- LogP:7.84410
- Storage Temp.:−20°C
- Solubility.:≤25mg/ml in DMSO;50mg/ml in dimethyl formamide
- XLogP3:8.2
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:16
- Exact Mass:448.26135963
- Heavy Atom Count:33
- Complexity:713
- Purity/Quality:
-
98%Min *data from raw suppliers
7-HC-arachidonate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:F,Xi
- Statements:
11-36/37/38
- Safety Statements:
7-16-26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC1=CC2=C(C=C1)C=CC(=O)O2
-
Uses
7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm). 7-HC-arachidonate is a PLA2 fluorogenic substrate for use in assays with phospholipid and Ca2+. It is for use with purified enzymes, as this substrate is nonspecific. 7-HC-arachidonate is ideal for drug discovery, HTS, and similar applications.
