2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid

Base Information

Chemical Name:2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid
CAS No.:78028-01-0
Molecular Formula:C₁₇H₁₆N₂O₅
Molecular Weight:328.324
Hs Code.:
DSSTox Substance ID:DTXSID101158958
Wikidata:Q27167240
Mol file:78028-01-0.mol

Synonyms:cay10397;78028-01-0;5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid;2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid;2-[5-[(4-ethoxycarbonylphenyl)diazenyl]-2-hydroxyphenyl]acetic acid;SCHEMBL10834750;CHEBI:95355;CHEBI:138839;5-Benzolazo-2-oxy-hydrozimtsaeure;DTXSID101158958;HMS3649K05;CAY10397, >98%, solid;AKOS040748087;SR-01000946578;SR-01000946578-1;Q27167240;(5-{(E)-[4-(ethoxycarbonyl)phenyl]diazenyl}-2-hydroxyphenyl)acetic acid;5-[2-[4-(Ethoxycarbonyl)phenyl]diazenyl]-2-hydroxybenzeneacetic acid

Suppliers and Price of 2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
CAY10397 >98%, solid
1mg
$ 188.00

Cayman Chemical
CAY10397 ≥98%
10mg
$ 399.00

Cayman Chemical
CAY10397 ≥98%
5mg
$ 225.00

Cayman Chemical
CAY10397 ≥98%
1mg
$ 51.00

Cayman Chemical
CAY10397 ≥98%
25mg
$ 871.00

AK Scientific
2-[3-[(4-Ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]aceticAcid
10mg
$ 596.00

Total 7 raw suppliers

Chemical Property of 2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid

Chemical Property:

PSA：108.55000
LogP:3.61140
Storage Temp.:−20°C
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:328.10592162
Heavy Atom Count:24
Complexity:460

Purity/Quality:

99% ^*data from raw suppliers

CAY10397 >98%, solid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)N=NC2=CC(=C(C=C2)O)CC(=O)O
Uses Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 μM. CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo.[Cayman Chemical]

Technology Process of 2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid

There total 1 articles about 2-[3-[(4-ethoxycarbonylphenyl)hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienyl]acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: