2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate

Base Information

• Chemical Name: 2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate
• CAS No.: 43042-79-1
• Molecular Formula: C₂₃H₄₀O₇
• Molecular Weight: 428.566
• DSSTox Substance ID: DTXSID20693998
• Mol file: 43042-79-1.mol

Synonyms:DTXSID20693998;Prostaglandin F2.alpha.-1-glyceryl ester;2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate

Chemical Property of 2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate

Chemical Property:

• PSA: 127.45000
• LogP: 1.85470
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 16
• Exact Mass: 428.27740361
• Heavy Atom Count: 30
• Complexity: 520

Purity/Quality:

99% ^*data from raw suppliers

Prostaglandin F2α-1-glyceryl ester ≥98% (as a 9:1 mixture of the 2- and 1-glyceryl esters) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)OCC(CO)O)O)O)O
• Uses: 2-Arachidonoyl glycerol (2-AG; ) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.

Technology Process of 2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate

There total 2 articles about 2,3-Dihydroxypropyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

C53H110O7Si5 → 1-ent-15(RS)-15-F2t-isoprostanoyl-sn-glycerol (43042-79-1)

Guidance literature:

With tetrabutyl ammonium fluoride;

DOI:10.1080/10715762.2016.1250262

Reference yield:

C38H76O5Si3 → 1-ent-15(RS)-15-F2t-isoprostanoyl-sn-glycerol (43042-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide; dmap

2: tetrabutyl ammonium fluoride

With dmap; tetrabutyl ammonium fluoride; dicyclohexyl-carbodiimide;

DOI:10.1080/10715762.2016.1250262

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 43042-79-1 9ALPHA-11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send