4,5-Diaminofluorescein

Base Information

Chemical Name:4,5-Diaminofluorescein
CAS No.:205391-01-1
Molecular Formula:C₂₀H₁₄N₂O₅
Molecular Weight:362.342
Hs Code.:
European Community (EC) Number:634-985-9
DSSTox Substance ID:DTXSID60443252
Nikkaji Number:J974.002C
Wikidata:Q82260985
Mol file:205391-01-1.mol

Synonyms:4,5-diaminofluorescein;DAF-2 (chromophore)

Suppliers and Price of 4,5-Diaminofluorescein

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DAF-2
2.5mg
$ 670.00

Sigma-Aldrich
4,5-Diaminofluorescein 5 mM in DMSO, ≥97% (HPLC)
1mg
$ 575.00

Sigma-Aldrich
4,5-Diaminofluorescein-Isopropanol adduct (1:2) powder
1mg
$ 575.00

Sigma-Aldrich
DAF-2
1mg-m
$ 451.00

Sigma-Aldrich
DAF-2-CAS205391-01-1-Calbiochem Ahighlysensitiveandspecificfluorescentindicatorforthedirectdetectiono
1 mg
$ 432.90

Cayman Chemical
DAF-2 ≥98%
1mg
$ 384.00

Cayman Chemical
DAF-2 ≥98%
500μg
$ 216.00

Cayman Chemical
DAF-2 ≥98%
250μg
$ 114.00

Cayman Chemical
DAF-2 ≥98%
100μg
$ 48.00

American Custom Chemicals Corporation
DAF-2 95.00%
1MG
$ 1001.73

Total 11 raw suppliers

Chemical Property of 4,5-Diaminofluorescein

Chemical Property:

PSA：128.03000
LogP:3.99260
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:362.09027155
Heavy Atom Count:27
Complexity:589

Purity/Quality:

99% ^*data from raw suppliers

DAF-2 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn,Xi
Statements: 22-36/37/38
Safety Statements: 23-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1O)OC3=C(C24C5=CC(=C(C=C5C(=O)O4)N)N)C=CC(=C3)O
Description DAF-2 is a sensitive fluorescent indicator commonly used for the detection of nitric oxide (NO). It reacts with NO in the presence of oxygen to yield the highly fluorescent triazolofluorescein (DAF-2T). Fluorescence is monitored using excitation and emission wavelengths of 485 and 538 nM, respectively. At neutral pH the detection limit for NO is 2-5 nM.
Uses DAF-2 is highly sensitive reagent for NO detection and determination of nitric oxide synthase activity. Fluorescent detector of nitric oxide in culture medium, tissue sections and biopsy cells.

Technology Process of 4,5-Diaminofluorescein

There total 2 articles about 4,5-Diaminofluorescein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%