1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE

Base Information

Chemical Name:1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE
CAS No.:13261-27-3
Molecular Formula:C₂₀H₃₆O₄
Molecular Weight:340.503
Hs Code.:
Mol file:13261-27-3.mol

Synonyms:1,3-Cyclopentanediol,4-(7-hydroxy-2-heptenyl)-5-(3-hydroxy-1-octenyl)- (8CI);2-Decarboxy-2-hydroxymethylprostaglandin F2a; AGN 190910; PGF2a alcohol; ZK67217

Suppliers and Price of 1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Prostaglandin F2α Alcohol ≥98%
10mg
$ 408.00

Cayman Chemical
Prostaglandin F2α Alcohol ≥98%
5mg
$ 230.00

Cayman Chemical
Prostaglandin F2α Alcohol ≥98%
1mg
$ 41.00

AK Scientific
1,9alpha,11alpha,15S-Tetrahydroxyprosta-5z,13e-diene
10mg
$ 650.00

Total 7 raw suppliers

Chemical Property of 1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE

Chemical Property:

Boiling Point:496.0±45.0 °C(Predicted)
PKA:14.59±0.70(Predicted)
PSA：80.92000
Density:1.097±0.06 g/cm3(Predicted)
LogP:2.95060

Purity/Quality:

98%min ^*data from raw suppliers

Prostaglandin F2α Alcohol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE

There total 5 articles about 1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 80559-59-7
10α,11α-epoxy-11-deoxyprostaglandin F_2α methyl ester

: 80559-61-1
(1S,2R,3R,4R)-3-((Z)-7-Hydroxy-hept-2-enyl)-4-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentane-1,2-diol

: 13261-27-3
1-decarboxy-1-hydroxymethylprostaglandin F_2α

: 80559-62-2
10α,11α-epoxy-1-decarboxy-1-hydroxymethyl-PGF_2α

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; 1.) room temperature, 2 h, 2.) 40 deg C, 2 h;
DOI:10.1021/ja00370a029

Reference yield:

: 38310-84-8
(Z)-7-[(1S,2R,3R,5S)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-4-oxo-6-oxa-bicyclo[3.1.0]hex-3-yl]-hept-5-enoic acid methyl ester

: 13261-27-3
1-decarboxy-1-hydroxymethylprostaglandin F_2α

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / sodium borohydride / methanol / 2 h / Ambient temperature

2: 38 percent / lithium aluminum hydride / diethyl ether / 1.) room temperature, 2 h, 2.) 40 deg C, 2 h

With sodium tetrahydroborate; lithium aluminium tetrahydride; In methanol; diethyl ether;
DOI:10.1021/ja00370a029

Reference yield:

: 31753-19-2
(5Z,13E)-15-hydroxy-9-oxoprosta 5,10,13 trien-1-oic acid

: 13261-27-3
1-decarboxy-1-hydroxymethylprostaglandin F_2α

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) hexamethyldisilazane, 2.) aq. hydrogen peroxide, lithium hydroxide / 1.) THF, room temperature, 4 h, 2.) isopropyl alcohol, -40 deg C, 30 min, -25 deg C, 3 h

2: hydrochloric acid

3: 59 percent / sodium borohydride / methanol / 2 h / Ambient temperature

4: 38 percent / lithium aluminum hydride / diethyl ether / 1.) room temperature, 2 h, 2.) 40 deg C, 2 h

With hydrogenchloride; lithium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane; In methanol; diethyl ether;
DOI:10.1021/ja00370a029