(2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester

Base Information

• Chemical Name: (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester
• CAS No.: 859979-88-7
• Molecular Formula: C₁₂H₁₂O₆
• Molecular Weight: 252.224
• Mol file: 859979-88-7.mol

Synonyms:(2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester

Chemical Property of (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester

There total 2 articles about (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

coumarandione (4732-72-3) → (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester (859979-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; water / Erwaermen der erhaltenen Loesung von <2-Hydroxy-phenyl>-glyoxylsaeure mit Bromessigsaeure-aethylester und mit aethanol. Natriumaethylat und Erwaermen des mit Wasser versetzten Reaktionsgemisches

2: diethyl ether

With diethyl ether; ethanol; water;

DOI:10.1002/hlca.193702001127

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (2-carboxymethoxy-phenyl)-glyoxylic acid (93334-77-1) → (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester (859979-88-7)

Guidance literature:

With diethyl ether;

DOI:10.1002/hlca.193702001127

Reference yield:

(2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester (859979-88-7) → 1-benzofurane (271-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium; diethyl ether / Erwaermen des Reaktionsgemisches mit Natriumaethylat in Aethanol und anschliessend mit Wasser

2: 270 °C

3: copper; quinoline

With quinoline; diethyl ether; sodium; copper;

DOI:10.1002/hlca.193702001127

upstream raw materials:

diazomethane

(2-carboxymethoxy-phenyl)-glyoxylic acid

coumarandione

Downstream raw materials:

1-benzofurane

benzofurane-3-carboxylic acid

benzo[b]furan-3-carbonyl chloride

2-(3-benzofuranyl)acetic acid