1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

Base Information

Chemical Name:1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole
CAS No.:1047657-72-6
Molecular Formula:C₁₉H₁₇BrF₃NO
Molecular Weight:412.249
Hs Code.:

Synonyms:1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

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Technology Process of 1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

There total 1 articles about 1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 128259-44-9
1-benzyl-2,5-dihydro-3-hydroxymethyl-1H-pyrrole

: 81107-97-3
2-bromo-4-(trifluoromethyl)phenol

: 1047657-72-6
1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 50 ℃; Inert atmosphere;

Reference yield: 51.8%

: 1047657-72-6
1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole

: 1047657-73-7
1'-benzyl-5-(trifluoromethyl)spiro[1-benzofuran-3,3'-pyrrolidine]

Guidance literature:: 1-benzyl-3-{[2-bromo-4-(trifluoromethyl)phenoxy]methyl}-2,5-dihydro-1H-pyrrole; With tri-n-butyl-tin hydride; In toluene; for 0.5h; Reflux;

With 2,2'-azobis(isobutyronitrile); In toluene; Inert atmosphere; Reflux;

With potassium fluoride; In diethyl ether; water; at 20 - 30 ℃; for 4h;