4-(Triazol-1-ylmethyl)phenol

Base Information

Chemical Name:4-(Triazol-1-ylmethyl)phenol
CAS No.:99590-27-9
Molecular Formula:C₉H₉N₃O
Molecular Weight:175.19
Hs Code.:
DSSTox Substance ID:DTXSID901285462
Nikkaji Number:J358.218C

Synonyms:99590-27-9;SCHEMBL4564456;DTXSID901285462;4-(1H-1,2,3-Triazol-1-ylmethyl)phenol

Suppliers and Price of 4-(Triazol-1-ylmethyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Triazol-1-ylmethyl)phenol

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:175.074561919
Heavy Atom Count:13
Complexity:157

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=CN=N2)O

Technology Process of 4-(Triazol-1-ylmethyl)phenol

There total 8 articles about 4-(Triazol-1-ylmethyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17271-88-4
p-nitrobenzyl azide

: 99590-27-9
1-(p-hydroxy-benzyl)-1H-1,2,3-triazole

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / benzene / 24 h / Heating

2: 79 percent / KOH / ethanol / 1 h / 60 °C

3: 95 percent / 12M HCl / dimethylformamide; H₂O / 45 h / Heating

4: 86 percent / dimethylformamide / 1 h / Heating

5: 94 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

6: NaNO₂ / 1.) aq. H₂SO₄, 0-3 grad C then roomtemp. 30 min; 2.) 90 grad C, 30 min

With hydrogenchloride; potassium hydroxide; hydrogen; sodium nitrite; palladium on activated charcoal; In ethanol; water; N,N-dimethyl-formamide; benzene;

Reference yield:

: 99590-18-8
dimethyl 1-(4-nitrobenzyl)-1H-1,2,3-triazole-4,5-dicarboxylate

: 99590-27-9
1-(p-hydroxy-benzyl)-1H-1,2,3-triazole

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / KOH / ethanol / 1 h / 60 °C

2: 95 percent / 12M HCl / dimethylformamide; H₂O / 45 h / Heating

3: 86 percent / dimethylformamide / 1 h / Heating

4: 94 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

5: NaNO₂ / 1.) aq. H₂SO₄, 0-3 grad C then roomtemp. 30 min; 2.) 90 grad C, 30 min

With hydrogenchloride; potassium hydroxide; hydrogen; sodium nitrite; palladium on activated charcoal; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 99590-19-9
ethyl 1-(4-nitrobenzyl)-1H-1,2,3-triazole-4-carboxylate

: 99590-27-9
1-(p-hydroxy-benzyl)-1H-1,2,3-triazole

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / KOH / ethanol / 3 h / Ambient temperature

2: 86 percent / dimethylformamide / 1 h / Heating

3: 94 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

4: NaNO₂ / 1.) aq. H₂SO₄, 0-3 grad C then roomtemp. 30 min; 2.) 90 grad C, 30 min

With potassium hydroxide; hydrogen; sodium nitrite; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;