tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate

Base Information

• Chemical Name: tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate
• CAS No.: 1389326-95-7
• Molecular Formula: C₂₄H₂₅ClN₂O₂
• Molecular Weight: 408.928

Synonyms:tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate

Chemical Property of tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate

Chemical Property:

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Technology Process of tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate

There total 1 articles about tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 1-(2-(4-chlorophenyl)-1-oxobutan-2-yl)-1H-indol-4-ylcarbamate (1389326-58-2) + dimethyl 1-(1-diazo-2-oxopropyl)phosphonate (90965-06-3) → tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate (1389326-95-7)

Guidance literature:

In methanol; at 20 ℃; for 4h;

Reference yield:

tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate (1389326-95-7) → tert-butyl 1-(3-(4-chlorophenyl)pentan-3-yl)-1H-indol-4-ylcarbamate (1389327-02-9)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

tert-butyl 1-(3-(4-chlorophenyl)pent-1-yn-3-yl)-1H-indol-4-ylcarbamate (1389326-95-7) → tert-butyl 1-(3-(4-chlorophenyl)pent-1-en-3-yl)-1H-indol-4-ylcarbamate (1389327-04-1)

Guidance literature:

With hydrogen; Lindlar's catalyst; In methanol; Inert atmosphere;

upstream raw materials:

tert-butyl 1-(2-(4-chlorophenyl)-1-oxobutan-2-yl)-1H-indol-4-ylcarbamate

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

Downstream raw materials:

methyl 4-(4-(tert-butoxycarbonylamino)-1H-indol-1-yl)-4-(4-chlorophenyl)hex-2-ynoate

tert-butyl 1-(1-(4-chlorophenyl)-1-(2H-1,2,3-triazol-4-yl)propyl)-1H-indol-4-ylcarbamate

tert-butyl 1-(1-(4-chlorophenyl)-1-(2-ethyl-2H-1,2,3-triazol-4-yl)propyl)-1H-indol-4-ylcarbamate

methyl 4-(4-(tert-butoxycarbonylamino)-1H-indol-1-yl)-4-(4-chlorophenyl)hexanoate

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