Technology Process of (2R,3S)-(+)-1-bromo-2-methylbutan-3-ol benzylether
There total 4 articles about (2R,3S)-(+)-1-bromo-2-methylbutan-3-ol benzylether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; lithium bromide; diethylazodicarboxylate;
In
tetrahydrofuran;
at 0 ℃;
for 6h;
DOI:10.1016/S0040-4020(01)89828-8
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 94 percent / trifluoromethane sulfonic acid / cyclohexane; CH2Cl2 / 3 h
2: 60 percent / DIBAH / 1.) -78 deg C, 1 h, 2.) 0 deg C, 5 h,
3: 80 percent / diethyl azodicarboxylate, triphenylphosphine, LiBr / tetrahydrofuran / 6 h / 0 °C
With
trifluorormethanesulfonic acid; diisobutylaluminium hydride; triphenylphosphine; lithium bromide; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; cyclohexane;
DOI:10.1016/S0040-4020(01)89828-8
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 94 percent / trifluoromethane sulfonic acid / cyclohexane; CH2Cl2 / 3 h
2: 60 percent / DIBAH / 1.) -78 deg C, 1 h, 2.) 0 deg C, 5 h,
3: 80 percent / diethyl azodicarboxylate, triphenylphosphine, LiBr / tetrahydrofuran / 6 h / 0 °C
With
trifluorormethanesulfonic acid; diisobutylaluminium hydride; triphenylphosphine; lithium bromide; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; cyclohexane;
DOI:10.1016/S0040-4020(01)89828-8
