dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Base Information

Chemical Name:dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate
CAS No.:917029-94-8
Molecular Formula:C₄₉H₆₁N₂O₂₂PS
Molecular Weight:1093.06
Hs Code.:

dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Synonyms:dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Suppliers and Price of dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

There total 17 articles about dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122210-01-9,122210-05-3,145416-95-1,146864-65-5,114360-77-9
1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranose

: 917029-94-8
dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 7 steps

1: 96 percent / HBr; AcOH / CH₂Cl₂ / 4 h / 0 - 20 °C

2: 55 percent / 4 Angstroem molecular sieves; AgOTf / CH₂Cl₂

3: ZnCl₂; AcOH

4: 2.1 g / AcOH; Zn / tetrahydrofuran

5: 92 percent / H₂ / Pd/C / tetrahydrofuran; methanol / 2 h / 20 °C

6: tetrazole / acetonitrile / 4 h / 20 °C

7: 1.5 g / aq. hydrogen peroxide / tetrahydrofuran / 2 h / -80 - 20 °C

With 1H-tetrazole; 4 A molecular sieve; hydrogen bromide; hydrogen; dihydrogen peroxide; silver trifluoromethanesulfonate; acetic acid; zinc(II) chloride; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1135/cccc20051615

Reference yield:

: 914642-50-5
benzyl 2-acetamido-6-O-benzyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranoside

: 917029-94-8
dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 6 steps

1: 55 percent / 4 Angstroem molecular sieves; AgOTf / CH₂Cl₂

2: ZnCl₂; AcOH

3: 2.1 g / AcOH; Zn / tetrahydrofuran

4: 92 percent / H₂ / Pd/C / tetrahydrofuran; methanol / 2 h / 20 °C

5: tetrazole / acetonitrile / 4 h / 20 °C

6: 1.5 g / aq. hydrogen peroxide / tetrahydrofuran / 2 h / -80 - 20 °C

With 1H-tetrazole; 4 A molecular sieve; hydrogen; dihydrogen peroxide; silver trifluoromethanesulfonate; acetic acid; zinc(II) chloride; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1135/cccc20051615

Reference yield:

: 78246-81-8
benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside

: 917029-94-8
dibenzyl 3,4,6-tri-O-acethyl-2-deoxy-2-acetamido-β-D-glucopyranosyl-(1->4)-2-acetamido-6-O-acetyl-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 9 steps

1.1: NaH / dioxane / 2 h / 95 °C

1.2: 80 percent / dioxane / 3 h / 60 °C

2.1: 84 percent / DMAP; EDCl / CH₂Cl₂

3.1: 91 percent / triflic acid; triethylsilane / CH₂Cl₂ / 1 h / -78 °C

4.1: 55 percent / 4 Angstroem molecular sieves; AgOTf / CH₂Cl₂

5.1: ZnCl₂; AcOH

6.1: 2.1 g / AcOH; Zn / tetrahydrofuran

7.1: 92 percent / H₂ / Pd/C / tetrahydrofuran; methanol / 2 h / 20 °C

8.1: tetrazole / acetonitrile / 4 h / 20 °C

9.1: 1.5 g / aq. hydrogen peroxide / tetrahydrofuran / 2 h / -80 - 20 °C

With 1H-tetrazole; triethylsilane; dmap; trifluorormethanesulfonic acid; 4 A molecular sieve; hydrogen; dihydrogen peroxide; silver trifluoromethanesulfonate; sodium hydride; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc(II) chloride; zinc; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; acetonitrile;
DOI:10.1135/cccc20051615