HEXAHYDROPYRIDAZINE DIHYDROCHLORIDE

Base Information

• Chemical Name: HEXAHYDROPYRIDAZINE DIHYDROCHLORIDE
• CAS No.: 124072-89-5
• Molecular Formula: C₄H₁₀N₂*2ClH
• Molecular Weight: 159.059
• Hs Code.: 2933990090
• Mol file: 124072-89-5.mol

Synonyms:Tetrahydropyridazine dihydrochloride;Pyridazine,hexahydro-, dihydrochloride (9CI);Hexahydropyridazine dihydrochloride;

Chemical Property of HEXAHYDROPYRIDAZINE DIHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.242mmHg at 25°C
• Melting Point: 135-137℃
• Boiling Point: 202.7 °C at 760 mmHg
• Flash Point: 76.4 °C
• PSA: 24.06000
• LogP: 2.13600
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

HexahydropyridazineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Hexahydropyridazine Dihydrochloride is a useful reagent for organic synthesis and other chemical processes. It is used as a reagent in the synthesis of completely hydrogenated dipiperidazino tetrazine, tetrazepine and tetrazone derivatives.

Technology Process of HEXAHYDROPYRIDAZINE DIHYDROCHLORIDE

There total 4 articles about HEXAHYDROPYRIDAZINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,4-dibromo-butane (110-52-1) → tetrahydropyridazine dihydrochloride (89990-53-4,124072-89-5,873221-58-0)

Guidance literature:

t-butoxycarbonylhydrazine; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h;

1,4-dibromo-butane; In N,N-dimethyl-formamide;

With hydrogenchloride; In 1,4-dioxane; diethyl ether; at 20 ℃; for 1h;

Reference yield: 95.3%

→ tetrahydropyridazine dihydrochloride (89990-53-4,124072-89-5,873221-58-0)

Guidance literature:

Reference yield: 95.0%

tert-butyl 2-[(tert-butyl)oxycarbonyl]perhydropyridazine-1-carboxylate (340256-13-5) → tetrahydropyridazine dihydrochloride (89990-53-4,124072-89-5,873221-58-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

DOI:10.1016/j.tetlet.2008.03.080

upstream raw materials:

tert-butyl 2-[(tert-butyl)oxycarbonyl]perhydropyridazine-1-carboxylate

1,4-dibromo-butane

tetrahydropyridazine-1,2-dicarbaldehyde

Downstream raw materials:

(R)-[3-oxo-3-(tetrahydropyridazin-1-yl)-1-(2,4,5-trifluorobenzyl)propyl]carbamic acid tert-butyl ester

Refernces

• 1、 -. "HERBICIDAL BENZOXAZINONES". Page/Page column 87; 88. . Retrieved 2012/04/17.
• 2、 Suzuki, Ichiro,Hirata, Ai,Takeda, Kei. "Development of cyclic hydrazine and hydrazide type organocatalyst-mechanistic aspects of cyclic hydrazine/hydrazide-catalyzed diels-alder reactions". scheme or table. p. 851 - 863. Retrieved 2009/12/01.