C₄₉H₆₄O₃

Base Information

• Chemical Name: C₄₉H₆₄O₃
• CAS No.: 1370028-11-7
• Molecular Formula: C₄₉H₆₄O₃
• Molecular Weight: 701.045
• Mol file: 1370028-11-7.mol

Synonyms:C₄₉H₆₄O₃

Chemical Property of C₄₉H₆₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₆₄O₃

There total 14 articles about C₄₉H₆₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C49H66O3 → C49H64O3 (1370028-11-7)

Guidance literature:

With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In acetonitrile; at 20 ℃; for 6h; Molecular sieve; Inert atmosphere;

DOI:10.1248/cpb.60.137

Reference yield:

C41H47NO4S (1370028-21-9) → C49H64O3 (1370028-11-7)

Guidance literature:

Multi-step reaction with 13 steps

1.1: toluene / 7.5 h / 120 °C / Inert atmosphere

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere

2.2: -78 °C / Inert atmosphere

3.1: Crabtree's catalyst; hydrogen / dichloromethane / 48 h / 20 °C / Inert atmosphere

4.1: trimethylaluminum / hexane; dichloromethane / 0.5 h / 0 °C / Inert atmosphere

4.2: 1 h / 0 °C / Inert atmosphere

5.1: tert.-butyl lithium / tetrahydrofuran; diethyl ether; pentane / 0.67 h / -78 °C / Inert atmosphere

5.2: 1.5 h / Inert atmosphere

6.1: zinc(II) chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

7.1: lithium aluminium tetrahydride / diethyl ether / 0.25 h / 0 °C / Inert atmosphere

8.1: sodium hydride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

9.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C / Inert atmosphere

9.2: 0.08 h / 0 °C / Inert atmosphere

10.1: 0.5 h / 0 °C / Inert atmosphere

11.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / toluene / 0.5 h / 90 °C / Inert atmosphere

12.1: bromocatecholborane / dichloromethane / 1 h / -78 °C / Inert atmosphere

13.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / acetonitrile / 6 h / 20 °C / Molecular sieve; Inert atmosphere

With lithium aluminium tetrahydride; n-butyllithium; tetrapropylammonium perruthennate; Crabtree's catalyst; 2,2'-azobis(isobutyronitrile); bromocatecholborane; hydrogen; trimethylaluminum; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; sodium hydride; 4-methylmorpholine N-oxide; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene; acetonitrile; pentane; 6.1: Diels-Alder reaction;

DOI:10.1248/cpb.60.137

Reference yield:

C51H70O4 (1370028-10-6) → C49H64O3 (1370028-11-7)

Guidance literature:

Multi-step reaction with 2 steps

1: bromocatecholborane / dichloromethane / 1 h / -78 °C / Inert atmosphere

2: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / acetonitrile / 6 h / 20 °C / Molecular sieve; Inert atmosphere

With tetrapropylammonium perruthennate; bromocatecholborane; 4-methylmorpholine N-oxide; In dichloromethane; acetonitrile;

DOI:10.1248/cpb.60.137

upstream raw materials:

C₅₁H₇₀O₄

C₄₁H₄₇NO₄S

C₅₃H₇₂O₅S₂

C₄₁H₄₇NO₄S

Downstream raw materials:

C₅₀H₆₆O₂