POTASSIUM FLUORIDE

Base Information

• Chemical Name: POTASSIUM FLUORIDE
• CAS No.: 12178-06-2
• Molecular Formula: FK
• Molecular Weight: 58.1
• Mol file: 12178-06-2.mol

Synonyms:FK

Chemical Property of POTASSIUM FLUORIDE

Chemical Property:

• Vapor Pressure: 922mmHg at 25°C
• Melting Point: 858 °C(lit.)
• Boiling Point: 19.5°C at 760 mmHg
• PSA: 0.00000
• LogP: -2.99600
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: 92.3 g/100 mL (18℃)

Purity/Quality:

99% ^*data from raw suppliers

POTASSIUM FLUORIDE ON ALUMINA 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,C,Xn
• Hazard Codes: T,C,Xn
• Statements: 22-34-20/21/22-25-48/20-23/24/25
• Safety Statements: 45-36/37/39-28-27-26-24/25-36-36/37

MSDS Files:

SDS file from LookChem

Useful:

• General Description: Potassium fluoride (KF), also referred to as FK, serves as an efficient, green, and reusable catalyst when supported on alumina (Al?O?), particularly for solvent-free Michael reactions in the synthesis of N-alkyl sulfonamide derivatives. This catalytic system, often enhanced with tetrabutylammonium bromide (TBAB), offers high yields and selectivity while eliminating the need for organic solvents, aligning with sustainable chemistry principles. Its reusability after simple washing and compatibility with microwave irradiation further underscore its practicality for industrial applications.

Refernces

KF/Al2O3 as an efficient, green, and reusable catalytic system for the solvent-free synthesis of N-Alkyl derivatives of sulfonamides via michael reactions

10.1080/10426500802274625

The study presents an efficient, green, and reusable catalytic system using KF/Al2O3 for the solvent-free synthesis of N-alkyl derivatives of sulfonamides via Michael reactions. The process is conducted under microwave irradiation without the need for organic solvents, making it environmentally friendly and cost-effective. The researchers optimized the reaction conditions and found that the use of KF/Al2O3 and tetrabutylammonium bromide (TBAB) significantly improved the yield and selectivity of the desired N-alkylated sulfonamides. The method was effective with various α,β-unsaturated esters and sulfonamides, demonstrating broad applicability. The catalyst could be reused multiple times after simple washing, showing its potential for industrial applications. The study emphasizes the importance of green chemistry practices and the role of microwave irradiation in accelerating reaction rates and improving outcomes.