ALPHA-KETOBUTYRIC ACID SODIUM SALT

Base Information

• Chemical Name: ALPHA-KETOBUTYRIC ACID SODIUM SALT
• CAS No.: 2013-26-5
• Molecular Formula: C4H6 O3 . Na
• Molecular Weight: 124.072
• Hs Code.: 29183000
• Mol file: 2013-26-5.mol

Synonyms:Butanoicacid, 2-oxo-, sodium salt (9CI); Butyric acid, 2-oxo-, sodium salt (8CI);2-Oxobutyric acid sodium salt; Sodium 2-oxobutyrate; Sodium a-ketobutyrate

Chemical Property of ALPHA-KETOBUTYRIC ACID SODIUM SALT

Chemical Property:

• Vapor Pressure: 0.0331mmHg at 25°C
• Boiling Point: 177.8°Cat760mmHg
• Flash Point: 65°C
• PSA: 57.20000
• Density: 1.182g/cm³
• LogP: -1.28460
• Storage Temp.: 2-8°C
• Water Solubility.: very faint turbidity

Purity/Quality:

98%, ^*data from raw suppliers

Sodium 2-Oxobutyrate >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium 2-oxobutyrate can be used in the preparation of metal complexes such as lanthanide poly(imino carboxylate) complexes and half-sandwich complexes of (S)-1-amino-2-(methoxymethyl)-pyrrolidine. It can also be used in the synthesis of antiviral agents, 6-azapyrimidine-2′-deoxy-4′-thionucleosides.

Technology Process of ALPHA-KETOBUTYRIC ACID SODIUM SALT

There total 2 articles about ALPHA-KETOBUTYRIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-carbopropane-1,2,2-tricarboxylic acid trimethyl ester → 2-oxobutyric acid, sodium salt (2013-26-5)

Guidance literature:

1-carbopropane-1,2,2-tricarboxylic acid trimethyl ester; With methanesulfonic acid; In water; toluene; at 90 ℃; for 7h; Large scale;

With sodium hydrogencarbonate; In ethanol; at 20 ℃; for 3h; Large scale;

Reference yield: 92.0%

1-carbopropane-1,2,2-tricarboxylic acid triethyl ester → 2-oxobutyric acid, sodium salt (2013-26-5)

Guidance literature:

1-carbopropane-1,2,2-tricarboxylic acid triethyl ester; With hydrogenchloride; In water; at 60 ℃; for 7h; Large scale;

With sodium hydroxide; In methanol; at 20 ℃; for 1h; Large scale;

Reference yield: 95.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-oxobutyric acid, sodium salt (2013-26-5) → C5H7O4(1-)*Na(1+)

Guidance literature:

With nickel dichloride; In water; pH=7; Enzymatic reaction;

DOI:10.1021/acscatal.9b01646

Downstream raw materials:

(R)-2-hydroxy-butyric acid ; sodium-salt

C₅H₅Mo(CO)2OCOC(C₂H₅)NNHC₆H₅

C₅H₅Mo(CO)2OCOC(C₂H₅)NC₆H₅

[Ru(H)(CO)(P(C₆H₅)3)2(OOCC(C₂H₅)N(CH₂C₆H₅))]