(S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE

Base Information

Chemical Name:(S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE
CAS No.:672906-71-7
Molecular Formula:C10H12 F3 N
Molecular Weight:203.207
Hs Code.:2921499090
Mol file:672906-71-7.mol

Synonyms:S-NME-PTF-PEM;

Suppliers and Price of (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(S)-N-{1-[4-(trifluoromethyl)phenyl]ethyl}methylamine 98%
1 g
$ 495.00

American Custom Chemicals Corporation
(S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE 98.00%
1G
$ 1149.23

Total 11 raw suppliers

Chemical Property of (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE

Chemical Property:

Vapor Pressure:0.307mmHg at 25°C
Boiling Point:201.501°C at 760 mmHg
Flash Point:75.666°C
PSA：12.03000
Density:1.118g/cm³
LogP:3.37670

Purity/Quality:

97% ^*data from raw suppliers

(S)-N-{1-[4-(trifluoromethyl)phenyl]ethyl}methylamine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE

There total 3 articles about (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 672906-92-2
C₁₈H₂₀F₃N

: 672906-71-7,574731-05-8
(S)-N-methyl-1-(4-(trifluoromethyl)phenyl)ethan-1-amine

Guidance literature:: C₁₈H₂₀F₃N; With hydrogen; acetic acid; 5%-palladium/activated carbon; In methanol; water; at 60 ℃; for 13.5h; under 3750.38 Torr;

With sodium hydroxide; In water;

Reference yield:

: (E)-N-methyl-1-(4-(trifluoromethyl)phenyl)ethan-1-imine

: 672906-71-7,574731-05-8
(S)-N-methyl-1-(4-(trifluoromethyl)phenyl)ethan-1-amine

Guidance literature:: With C₃₂H₁₂BF₂₄^(1-)*C₃₃H₅₂IrN₃O₂P⁽¹⁺⁾; hydrogen; In dichloromethane; at -10 ℃; under 2250.23 Torr; enantioselective reaction;
DOI:10.1021/jacs.8b11547

Reference yield:

: 709-63-7
1-(4-trifluoromethylphenyl)ethanone

: 672906-71-7,574731-05-8
(S)-N-methyl-1-(4-(trifluoromethyl)phenyl)ethan-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 48 h / 20 °C / Inert atmosphere; Molecular sieve

2: C₃₂H₁₂BF₂₄^(1-)*C₃₃H₅₂IrN₃O₂P⁽¹⁺⁾; hydrogen / dichloromethane / -10 °C / 2250.23 Torr

With C₃₂H₁₂BF₂₄^(1-)*C₃₃H₅₂IrN₃O₂P⁽¹⁺⁾; hydrogen; In ethanol; dichloromethane;
DOI:10.1021/jacs.8b11547