5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Base Information

• Chemical Name: 5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate
• CAS No.: 679825-65-1
• Molecular Formula: C₂₇H₃₅NO₆
• Molecular Weight: 469.578
• Mol file: 679825-65-1.mol

Synonyms:5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Chemical Property of 5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

There total 1 articles about 5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

chemantane (20098-14-0) + (4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid (143615-03-6,143527-70-2) → 5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate (679825-65-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1023/B:RUJO.0000003160.87327.e1

Reference yield: 99.0%

5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate (679825-65-1) → (4S,5R)-3-tert-butyl-5-(4-hydroxyadamantyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Guidance literature:

With sodium tetrahydroborate; In methanol; diethyl ether; at 0 ℃;

DOI:10.1023/B:RUJO.0000003160.87327.e1

Reference yield:

5-(4-oxo-1-adamantyl) 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate (679825-65-1) → C19H23NO4

Guidance literature:

With formic acid; In water; at 25 ℃; for 2h;

DOI:10.1016/j.bmcl.2008.07.116

upstream raw materials:

chemantane

(4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid