N-(5-Ethoxy-2-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(5-Ethoxy-2-nitrophenyl)acetamide
• CAS No.: 116496-78-7
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.216
• DSSTox Substance ID: DTXSID40571461
• Wikidata: Q82459551
• Mol file: 116496-78-7.mol

Synonyms:N-(5-ETHOXY-2-NITROPHENYL)ACETAMIDE;116496-78-7;5-ethoxy-2-nitroacetanilide;SCHEMBL2776809;DTXSID40571461;UFINFVSGAFRMQZ-UHFFFAOYSA-N;N-(5-ethoxy-2-nitro-phenyl)acetamide;A803628

Chemical Property of N-(5-Ethoxy-2-nitrophenyl)acetamide

Chemical Property:

• Boiling Point: 440.6±35.0 °C(Predicted)
• Density: 1.282±0.06 g/cm3(Predicted)
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 224.07970687
• Heavy Atom Count: 16
• Complexity: 264

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC1=CC(=C(C=C1)[N+](=O)[O-])NC(=O)C

Technology Process of N-(5-Ethoxy-2-nitrophenyl)acetamide

There total 3 articles about N-(5-Ethoxy-2-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-ethoxyacetanilide (591-33-3) → N-(5-ethoxy-2-nitrophenyl)acetamide (116496-78-7)

Guidance literature:

With nitric acid; acetic anhydride;

DOI:10.1021/ja00865a031

Reference yield:

3-ethoxyacetanilide (591-33-3) → acetic acid-(3-ethoxy-4-nitro-anilide) (871895-08-8) + N-(5-ethoxy-2-nitrophenyl)acetamide (116496-78-7)

Guidance literature:

With nitric acid; acetic anhydride;

Reference yield:

3-ethoxyacetanilide (591-33-3) → acetic acid-(3-ethoxy-4-nitro-anilide) (871895-08-8) + N-(5-ethoxy-2-nitrophenyl)acetamide (116496-78-7) + acetic acid-(5-ethoxy-2,4-dinitro-anilide) (872819-78-8)

Guidance literature:

bei der Nitrierung;

upstream raw materials:

3-ethoxyacetanilide

Downstream raw materials:

5-ethoxy-2-nitroaniline

N-(5-hydroxy-2-nitrophenyl)acetamide

acetic acid-(5-ethoxy-2,4-dinitro-anilide)

2-amino-5-ethoxyacetanilide