D-Arginine amide dihydrochloride

Base Information

• Chemical Name: D-Arginine amide dihydrochloride
• CAS No.: 203308-91-2
• Molecular Formula: C₆H₁₅N₅O
• Molecular Weight: 173.218
• Hs Code.: 2925290090
• UNII: XUE0FE7GQB
• Nikkaji Number: J353.968G
• Mol file: 203308-91-2.mol

Synonyms:Pentanamide,2-amino-5-[(aminoiminomethyl)amino]-, (R)-;D-Argininamide;

Chemical Property of D-Arginine amide dihydrochloride

Chemical Property:

• Vapor Pressure: 2.03E-08mmHg at 25°C
• Boiling Point: 447.7oC at 760 mmHg
• PKA: 16.01±0.50(Predicted)
• Flash Point: 224.5oC
• PSA: 131.01000
• Density: 1.46±0.1 g/cm3(Predicted)
• LogP: 0.65380
• Storage Temp.: 2-8°C
• XLogP3: -2.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 173.12766012
• Heavy Atom Count: 12
• Complexity: 175

Purity/Quality:

98%,99%, ^*data from raw suppliers

D-Arginine amide dihydrochloride ≥ 98% (NMR) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(C(=O)N)N)CN=C(N)N
• Isomeric SMILES: C(C[C@H](C(=O)N)N)CN=C(N)N

Technology Process of D-Arginine amide dihydrochloride

There total 3 articles about D-Arginine amide dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-Arg-(Z)2-NH2 → L-arginine amide (2788-83-2,203308-91-2)

Guidance literature:

With hydrogen; palladium on activated charcoal;

Reference yield:

Nα,Nω,Nω'-Tris(benzyloxycarbonyl)-L-arginin (1947-42-8,20888-05-5) → L-arginine amide (2788-83-2,203308-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Et₃N, CHCl₃, (ii) NH₃, ClCO₂iBu, toluene

2: H₂ / Pd-C

With hydrogen; palladium on activated charcoal;

Reference yield:

→ L-arginine amide (2788-83-2,203308-91-2)

Guidance literature:

upstream raw materials:

N^α,N^ω,N^ω'-Tris(benzyloxycarbonyl)-L-arginin

Downstream raw materials:

(2S,3S,4S)-N-benzyloxycarbonyl-2-(((S)-arginineamidyl)methyl)-3,4-dihydroxypyrrolidine

(2R,3R,4R)-N-benzyloxycarbonyl-2-(((S)-arginineamidyl)methyl)-3,4-dihydroxypyrrolidine

Refernces

• 1、 -. "Peptide Tyrosinase Activators". . . Retrieved 2015/06/10.