(1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone

Base Information

• Chemical Name: (1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone
• CAS No.: 1214271-09-6
• Molecular Formula: C₁₉H₂₂O₄S
• Molecular Weight: 346.447
• Mol file: 1214271-09-6.mol

Synonyms:(1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone

Chemical Property of (1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone

There total 1 articles about (1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

PVS (5535-48-8) + 1-methoxy-4-{[(2R)-pent-4-en-2-yloxy]methyl}benzene (1176252-19-9) → (1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone (1214271-09-6)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 90 ℃; for 1h; Microwave irradiation; Inert atmosphere;

DOI:10.1039/b918233k

Reference yield:

(1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone (1214271-09-6) + trans-2-phenylvinylboronic acid (6783-05-7) + (2S)-1-(phenylmethoxy)but-3-en-2-ylamine (97682-96-7,99726-01-9,127505-65-1) → (3S,4R,6R,E)-3-((S)-1-(benzyloxy)but-3-en-2-ylamino)-6-(4-methoxybenzyloxy)-1-phenylhept-1-en-4-ol (1214271-10-9) + (3R,4R,6R,E)-3-((S)-1-(benzyloxy)but-3-en-2-ylamino)-6-(4-methoxybenzyloxy)-1-phenylhept-1-en-4-ol

Guidance literature:

(1E,4R)-4-[(4-methoxybenzyl)oxy]-pent-1-en-1-yl phenyl sulfone; With potassium osmate(VI) dihydrate; methanesulfonamide; potassium carbonate; potassium hexacyanoferrate(III); In water; tert-butyl alcohol; at 20 ℃; for 24h; Sonication;

trans-2-phenylvinylboronic acid; (2S)-1-(phenylmethoxy)but-3-en-2-ylamine; In dichloromethane; at 20 ℃; for 48h; optical yield given as %de; Inert atmosphere;

DOI:10.1039/b918233k

upstream raw materials:

PVS

1-methoxy-4-{[(2R)-pent-4-en-2-yloxy]methyl}benzene

Downstream raw materials:

(3S,4R,6R,E)-3-((S)-1-(benzyloxy)but-3-en-2-ylamino)-6-(4-methoxybenzyloxy)-1-phenylhept-1-en-4-ol