N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

Base Information

Chemical Name:N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester
CAS No.:83103-21-3
Molecular Formula:C₂₀H₃₀N₆O₇
Molecular Weight:466.494
Hs Code.:

N<sup>α</sup>-tert-butyloxycarbonyl-N<sup>G</sup>-nitroarginylglycine benzyl ester

Synonyms:N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

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Chemical Property of N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

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Technology Process of N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

There total 4 articles about N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 2188-18-3
Boc-Arg(NO₂)-OH

: benzyl glycinate benzenesulfonate

: 83103-21-3
N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

Guidance literature:: Boc-Arg(NO₂)-OH; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.333333h;

benzyl glycinate benzenesulfonate; With 4-methyl-morpholine; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1039/c5md00215j

Reference yield: 86.0%

: 2188-18-3
Boc-Arg(NO₂)-OH

: 1738-76-7
glycine benzyl ester p-toluenesulfonic acid salt

: 83103-21-3
N^α-tert-butyloxycarbonyl-N^G-nitroarginylglycine benzyl ester

Guidance literature:: Boc-Arg(NO₂)-OH; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.5h;

glycine benzyl ester p-toluenesulfonic acid salt; With 4-methyl-morpholine; In tetrahydrofuran; at 0 - 20 ℃; for 10h; pH=9;
DOI:10.2147/IJN.S212978