ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

Base Information

Chemical Name:ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate
CAS No.:643093-00-9
Molecular Formula:C₃₁H₃₁ClN₂O₃
Molecular Weight:515.052
Hs Code.:

Synonyms:ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

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Technology Process of ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

There total 2 articles about ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 643094-29-5
ethyl 6-{4-[2-(benzylamino)ethyl]phenyl}nicotinate hydrochloride

: 20697-04-5,53631-04-2,115648-90-3,62600-71-9
(R)-meta-chlorostyrene oxide

: 643093-00-9
ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

Guidance literature:: With triethylamine; In ethanol; for 48h; Heating;
DOI:10.1021/jm701324c

Reference yield:

: 643093-00-9
ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

Guidance literature:

Reference yield:

: 643093-00-9
ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate

: C₂₄H₂₅ClN₂O₃

Guidance literature:: ethyl 6-[4-(2-{benzyl[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)phenyl]nicotinate; With hydrogenchloride; In 1,4-dioxane;

With hydrogen; palladium on activated charcoal; In ethanol; chlorobenzene; Further stages.;
DOI:10.1021/jm701324c