Technology Process of C22H20N2O2
There total 5 articles about C22H20N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
samarium diiodide;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 0.25h;
DOI:10.1002/anie.201201905
- Guidance literature:
-
Multi-step reaction with 5 steps
1: trifluoroacetic acid / 0.5 h / 20 °C
2: triethylsilane / 2 h / 0 - 20 °C
3: (R)-3,3'-bis(3,5-dinitrophenyl)-1,1'-binaphthyl-2,2'-dicarboxylic acid / 1,3,5-trimethyl-benzene / 24 h / -20 °C / Molecular sieve
4: 2,2,2-trifluoroethanol; potassium carbonate / m-xylene / 24 h / -30 - 20 °C / Molecular sieve
5: samarium diiodide / tetrahydrofuran; methanol / 0.25 h / 20 °C
With
triethylsilane; samarium diiodide; 2,2,2-trifluoroethanol; (R)-3,3'-bis(3,5-dinitrophenyl)-1,1'-binaphthyl-2,2'-dicarboxylic acid; potassium carbonate; trifluoroacetic acid;
In
tetrahydrofuran; methanol; m-xylene; 1,3,5-trimethyl-benzene;
3: Ugi-type reaction;
DOI:10.1002/anie.201201905
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylsilane / 2 h / 0 - 20 °C
2: (R)-3,3'-bis(3,5-dinitrophenyl)-1,1'-binaphthyl-2,2'-dicarboxylic acid / m-xylene / 40 h / -30 °C / Molecular sieve
3: 2,2,2-trifluoroethanol; potassium carbonate / m-xylene / 24 h / -30 - 20 °C / Molecular sieve
4: samarium diiodide / tetrahydrofuran; methanol / 0.25 h / 20 °C
With
triethylsilane; samarium diiodide; 2,2,2-trifluoroethanol; (R)-3,3'-bis(3,5-dinitrophenyl)-1,1'-binaphthyl-2,2'-dicarboxylic acid; potassium carbonate;
In
tetrahydrofuran; methanol; m-xylene;
2: Ugi-type reaction;
DOI:10.1002/anie.201201905
