C₂₈H₄₄N₂O₁₁S

Base Information

• Chemical Name: C₂₈H₄₄N₂O₁₁S
• CAS No.: 1334173-67-9
• Molecular Formula: C₂₈H₄₄N₂O₁₁S
• Molecular Weight: 616.73
• Mol file: 1334173-67-9.mol

Synonyms:C₂₈H₄₄N₂O₁₁S

Chemical Property of C₂₈H₄₄N₂O₁₁S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₄₄N₂O₁₁S

There total 17 articles about C₂₈H₄₄N₂O₁₁S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C44H62N2O11SSi (1334173-73-7) → C28H44N2O11S (1334173-67-9)

Guidance literature:

With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201103550

Reference yield:

C25H30O3Si (1334173-57-7) → C28H44N2O11S (1334173-67-9)

Guidance literature:

Multi-step reaction with 13 steps

1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane / tetrahydrofuran / -78 - 0 °C / Inert atmosphere

1.2: 13 h / -78 °C / Inert atmosphere

2.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.1: dicobalt octacarbonyl / toluene / 1.5 h / 20 °C / Inert atmosphere

3.2: 12 h / 100 °C

4.1: tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine / dichloromethane / 15 h / 20 °C / Inert atmosphere

5.1: borane-THF; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

6.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

6.2: 0 - 20 °C / Inert atmosphere

7.1: sodium hydrogencarbonate / 1,2-dichloro-benzene / 10 h / 170 °C / Inert atmosphere

8.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere

8.2: -78 - 20 °C / Inert atmosphere

9.1: dimethylsulfide borane complex / tetrahydrofuran; dimethylsulfide / 12.5 h / 0 °C / Inert atmosphere

9.2: 10 h / 0 °C / Inert atmosphere

9.3: NaBO₃*4H₂O / 4 h / 20 °C / Inert atmosphere

10.1: triethylamine / dichloromethane / 4 h / 0 °C / Inert atmosphere

11.1: dmap / pyridine; dichloromethane / 0 - 20 °C / Inert atmosphere

12.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C / Inert atmosphere

13.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium borohydride; n-butyllithium; dicobalt octacarbonyl; borane-THF; dimethylsulfide borane complex; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; lithium hexamethyldisilazane; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; pyridine; dimethylsulfide; hexane; dichloromethane; N,N-dimethyl-formamide; 1,2-dichloro-benzene; toluene; mineral oil; 3.1: Pauson-Khand reaction / 3.2: Pauson-Khand reaction;

DOI:10.1002/anie.201103550

Reference yield:

C26H34O4Si → C28H44N2O11S (1334173-67-9)

Guidance literature:

Multi-step reaction with 14 steps

1.1: pyridinium p-toluenesulfonate / isopropyl alcohol; toluene / 28 - 80 °C / Inert atmosphere

2.1: N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane / tetrahydrofuran / -78 - 0 °C / Inert atmosphere

2.2: 13 h / -78 °C / Inert atmosphere

3.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

4.1: dicobalt octacarbonyl / toluene / 1.5 h / 20 °C / Inert atmosphere

4.2: 12 h / 100 °C

5.1: tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine / dichloromethane / 15 h / 20 °C / Inert atmosphere

6.1: borane-THF; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

7.2: 0 - 20 °C / Inert atmosphere

8.1: sodium hydrogencarbonate / 1,2-dichloro-benzene / 10 h / 170 °C / Inert atmosphere

9.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere

9.2: -78 - 20 °C / Inert atmosphere

10.1: dimethylsulfide borane complex / tetrahydrofuran; dimethylsulfide / 12.5 h / 0 °C / Inert atmosphere

10.2: 10 h / 0 °C / Inert atmosphere

10.3: NaBO₃*4H₂O / 4 h / 20 °C / Inert atmosphere

11.1: triethylamine / dichloromethane / 4 h / 0 °C / Inert atmosphere

12.1: dmap / pyridine; dichloromethane / 0 - 20 °C / Inert atmosphere

13.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C / Inert atmosphere

14.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium borohydride; n-butyllithium; dicobalt octacarbonyl; borane-THF; dimethylsulfide borane complex; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; lithium hexamethyldisilazane; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; pyridine; dimethylsulfide; hexane; dichloromethane; N,N-dimethyl-formamide; 1,2-dichloro-benzene; isopropyl alcohol; toluene; mineral oil; 4.1: Pauson-Khand reaction / 4.2: Pauson-Khand reaction;

DOI:10.1002/anie.201103550

upstream raw materials:

C₂₈H₃₄O₃Si

C₂₈H₃₈O₃Si

C₂₉H₃₈O₄Si

C₃₁H₄₂O₄Si₂

Downstream raw materials:

C₂₈H₄₂N₂O₁₀S

C₂₄H₃₄N₂O₈S

C₂₆H₃₄N₂O₉S