4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

Base Information

Chemical Name:4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone
CAS No.:1029360-07-3
Molecular Formula:C₁₉H₁₆F₃N₃O
Molecular Weight:359.351
Hs Code.:

Synonyms:4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

Chemical Property:

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Technology Process of 4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

There total 1 articles about 4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1029360-05-1
2-trifluoromethylphenyl-4-[5-(2-trimethylsilyl-1-ethynyl)pyridin-2-yl]piperazinomethanone

: 1029360-07-3
4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

Guidance literature:: With methanol; sodium hydroxide; water; at 20 ℃; for 2h;

Reference yield:

: 1029360-07-3
4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone

: 123-38-6
propionaldehyde

: 1029358-07-3
(4-[5-(3-hydroxy-1-pentynyl)-2-pyridyl]piperazino)-2-trifluoromethylphenylmethanone

Guidance literature:: 4-[5-(1-ethynyl)-2-pyridinyl]piperazino-2-trifluoromethylphenylmethanone; With n-butyllithium; In tetrahydrofuran; hexanes; at -70 ℃; for 0.25h;

propionaldehyde; In tetrahydrofuran; hexanes; at -70 ℃; for 0.333333h;

With water; In tetrahydrofuran; hexanes;