N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Base Information

Chemical Name:N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide
CAS No.:1374744-74-7
Molecular Formula:C₂₂H₁₆BrF₃N₄O₂S
Molecular Weight:537.36
Hs Code.:

Synonyms:N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Suppliers and Price of N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

There total 6 articles about N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₂₄BrF₃N₄O₄S

: 1374744-74-7
N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Guidance literature:: C₂₇H₂₄BrF₃N₄O₄S; With trifluoroacetic acid; In dichloromethane; for 1h;

With sodium hydrogencarbonate; In dichloromethane;
DOI:10.1016/j.bmc.2012.06.018

Reference yield:

: 1252678-97-9
5-(4'-Bromo-biphenyl-4-yl)-1-(4-nitro-phenyl)-3-trifluoromethyl-1H-pyrazole

: 1374744-74-7
N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: platinum(IV) oxide; hydrogen / ethanol

2: triethylamine / dichloromethane / 1 h / 25 °C

3: trifluoroacetic acid / dichloromethane / 1 h

With platinum(IV) oxide; hydrogen; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1016/j.bmc.2012.06.018

Reference yield:

: 5731-01-1
4-bromo-4'-acetylbiphenyl

: 1374744-74-7
N-{4-[5-(4'-Bromo-biphenyl-4-yl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-aminosulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydride / tetrahydrofuran / 5 h / 25 °C

2: hydrogenchloride / ethanol / Reflux

3: platinum(IV) oxide; hydrogen / ethanol

4: triethylamine / dichloromethane / 1 h / 25 °C

5: trifluoroacetic acid / dichloromethane / 1 h

With hydrogenchloride; platinum(IV) oxide; hydrogen; sodium hydride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/j.bmc.2012.06.018