(R)-2,2,2-Trifluoro-1-phenylethylamine HCl

Base Information

• Chemical Name: (R)-2,2,2-Trifluoro-1-phenylethylamine HCl
• CAS No.: 189350-64-9
• Molecular Formula: C₈H₈F₃N*ClH
• Molecular Weight: 211.614
• Hs Code.: 2921499090
• Mol file: 189350-64-9.mol

Synonyms:Benzenemethanamine, α-(trifluoromethyl)-, hydrochloride, (αR)- (9CI);Benzenemethanamine,α-(trifluoromethyl)-,hydrochloride, (R)-;

Chemical Property of (R)-2,2,2-Trifluoro-1-phenylethylamine HCl

Chemical Property:

• Vapor Pressure: 0.0356mmHg at 25°C
• Boiling Point: 237.7 °C at 760 mmHg
• Flash Point: 97.6 °C
• PSA: 26.02000
• LogP: 3.75100
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(R)-2,2,2-Trifluoro-1-phenylethanaminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-2,2,2-Trifluoro-1-phenylethylamine HCl

There total 15 articles about (R)-2,2,2-Trifluoro-1-phenylethylamine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-(((S)-2,2,2-trifluoro-1-phenylethyl)amino)-3-methylbutanamide (1190864-56-2) → (S)-2,2,2-trifluoro-1-phenylethan-1-amine hydrochloride (128404-37-5,189350-64-9)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 48h;

DOI:10.1002/anie.200902457

Reference yield: 97.0%

N-benzylidene(1-phenyl-2,2,2-trifluoroethyl)amine (119561-20-5) → (RS)-1-phenyl-2,2,2-trifluoroethylamine hydrochloride (13652-09-0,128404-37-5,189350-64-9)

Guidance literature:

With hydrogenchloride; In diethyl ether; Ambient temperature;

DOI:10.1021/jo960503g

Reference yield: 96.0%

N-benzylidene-2,2,2-trifluoro-1-(phenyl)ethylamine → (RS)-1-phenyl-2,2,2-trifluoroethylamine hydrochloride (13652-09-0,128404-37-5,189350-64-9)

Guidance literature:

With hydrogenchloride; In diethyl ether; for 4h; Ambient temperature;

DOI:10.1016/S0040-4039(00)76845-6

upstream raw materials:

[1-Phenyl-eth-(E)-ylidene]-(2,2,2-trifluoro-1-phenyl-ethyl)-amine

N-benzylidene(1-phenyl-2,2,2-trifluoroethyl)amine

2,2,2-Trifluoroacetophenone

N-(1-phenyl-2,2,2-trifluoroisopropylidene)benzylamine

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