2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

Base Information

Chemical Name:2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid
CAS No.:745020-24-0
Molecular Formula:C₃₂H₄₁N₃O₈
Molecular Weight:595.693
Hs Code.:

Synonyms:2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

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Chemical Property of 2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

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Technology Process of 2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

There total 1 articles about 2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 900174-06-3
(3-ethoxy-4-isopropoxyphenyl)boronic acid

: 745020-22-8
imidodicarbonic acid 2-(6-amino-1-isoquinolinyl)-1,3-bis(1,1-dimethylethyl)ester

: 298-12-4
Glyoxilic acid

: 745020-24-0
2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

Guidance literature:: In methanol; toluene; at 20 - 60 ℃; for 6h;

Reference yield:

: 745020-24-0
2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

: 918810-19-2
2-(1-Aminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethyl acetate; at 20 ℃;

Reference yield:

: 1006-64-0
2-(phenyl)pyrrolidine

: 745020-24-0
2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid

: C₄₂H₅₂N₄O₇

Guidance literature:: With 1-hydroxy-7-aza-benzotriazole; N,N-diisopropylmethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 20 ℃; for 4h;

upstream raw materials:

(3-ethoxy-4-isopropoxyphenyl)boronic acid

imidodicarbonic acid 2-(6-amino-1-isoquinolinyl)-1,3-bis(1,1-dimethylethyl)ester

Glyoxilic acid

Downstream raw materials:

2-(1-Aminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetic acid hydrochloride

C₄₇H₆₁N₅O₁₁S

N-(2-(cyclopropylsulfonyl)benzyl)-2-(1-aminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetamide trifluoroacetic acid salt

N-(2-(isopropylsulfonyl)benzyl)-2-(1-aminoisoquinolin-6-ylamino)-2-(3-ethoxy-4-isopropoxyphenyl)acetamide trifluoroacetic acid salt

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