Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate

Base Information

• Chemical Name: Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate
• CAS No.: 75964-11-3
• Molecular Formula: C₂₂H₃₀O₆S
• Molecular Weight: 422.543
• Mol file: 75964-11-3.mol

Synonyms:Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate

Chemical Property of Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate

There total 2 articles about Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-mesitylenesulphonyl chloride (773-64-8) + Methyl 7-(2,5-dioxocyclopentyl)heptanoate (67136-06-5) → Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate (75964-11-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; 1.) -15 deg C, 20 min, 2.) room temp., 1 h;

DOI:10.1002/cber.19801130911

Reference yield:

4-ketododecanedioic acid dimethyl ester (30828-10-5) → Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate (75964-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / sodium ethoxide / toluene / 0.5 h / Heating

2: 82 percent / Et₃N / tetrahydrofuran / 1.) -15 deg C, 20 min, 2.) room temp., 1 h

With sodium ethanolate; triethylamine; In tetrahydrofuran; toluene;

DOI:10.1002/cber.19801130911

Reference yield:

Methyl 7-<2-(mesitylenesulfonyloxy)-5-oxo-1-cyclopentenyl>heptanoate (75964-11-3) → 2-(6-methoxycarbonylhexyl)cyclopent-2-en-1-one (34546-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol / 2 h / Ambient temperature

2: (COOH)2, (COONa)2 / CHCl₃ / 3 h / Ambient temperature

With sodium tetrahydroborate; sodium oxalate; oxalic acid; In methanol; chloroform;

DOI:10.1002/cber.19801130911

upstream raw materials:

2-mesitylenesulphonyl chloride

Methyl 7-(2,5-dioxocyclopentyl)heptanoate

4-ketododecanedioic acid dimethyl ester

Downstream raw materials:

2-(6-methoxycarbonylhexyl)cyclopent-2-en-1-one