8-Methyl-decahydroquinoline

Base Information

• Chemical Name: 8-Methyl-decahydroquinoline
• CAS No.: 52601-69-1
• Molecular Formula: C₁₀H₁₉N
• Molecular Weight: 153.268
• DSSTox Substance ID: DTXSID701310275
• Nikkaji Number: J3.186.317A
• Mol file: 52601-69-1.mol

Synonyms:8-methyl-decahydroquinoline;52601-69-1;8-Methyldecahydroquinoline;8-methyl-1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline;Decahydro-8-methylquinoline;SCHEMBL3964863;DTXSID701310275;CCA60169;AKOS000183957;AKOS022488529;EN300-54599;Z317054150

Chemical Property of 8-Methyl-decahydroquinoline

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 153.151749610
• Heavy Atom Count: 11
• Complexity: 133

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCC2C1NCCC2

Technology Process of 8-Methyl-decahydroquinoline

There total 3 articles about 8-Methyl-decahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

8-methylquinoline (611-32-5) → 8-methyldecahydro-quinoline (52601-69-1) + 8-methyl-1,2,3,4-tetrahydroquinoline (52601-70-4)

Guidance literature:

With hydrogen; In neat (no solvent); at 80 ℃; for 15h; under 7500.75 Torr; chemoselective reaction; Autoclave;

DOI:10.1039/c6gc02782b

Reference yield:

8-methyl-1,2,3,4-tetrahydroquinoline (52601-70-4) → 8-methyldecahydro-quinoline (52601-69-1) + 8-methylquinoline (611-32-5) + 8-methyl-5,6,7,8-tetrahydroquinoline (52601-66-8)

Guidance literature:

With hydrogen; nickel; at 200 ℃; under 7600 Torr; Rate constant; or Ru/C, 100 atm, 150 deg C;

DOI:10.1246/bcsj.63.3167

Reference yield:

8-methylquinoline (611-32-5) → 8-methyldecahydro-quinoline (52601-69-1) + 8-methyl-1,2,3,4-tetrahydroquinoline (52601-70-4) + 8-methyl-5,6,7,8-tetrahydroquinoline (52601-66-8)

Guidance literature:

With hydrogen; nickel; at 200 ℃; under 7600 Torr; Rate constant; or Ru/C, 100 atm, 150 deg C;

DOI:10.1246/bcsj.63.3167

upstream raw materials:

8-methylquinoline

8-methyl-1,2,3,4-tetrahydroquinoline

Downstream raw materials:

8-methyl-1,2,3,4-tetrahydroquinoline

8-methylquinoline