ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

Base Information

Chemical Name:ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate
CAS No.:1586023-59-7
Molecular Formula:C₂₄H₃₉N₃O₄
Molecular Weight:433.591
Hs Code.:

Synonyms:ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

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Chemical Property of ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

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Technology Process of ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

There total 3 articles about ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 3376-24-7,68315-30-0
N-tert-butyl-α-phenylnitrone

: 1586023-52-0
ethyl 2-{[isopropyl(N-isopropylcarbamoyl)amino]methyl}acrylate

: 1586023-59-7
ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

Guidance literature:: In toluene; at 80 ℃; for 24h; regiospecific reaction; Inert atmosphere;
DOI:10.3184/174751913X13783169779948

Reference yield:

: 17435-72-2
ethyl 2-bromomethyl-2-propenoate

: 1586023-59-7
ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / chloroform

2: toluene / Inert atmosphere; Reflux

3: toluene / 24 h / 80 °C / Inert atmosphere

With triethylamine; In chloroform; toluene;
DOI:10.3184/174751913X13783169779948

Reference yield:

: 1586023-49-5
C₉H₁₇NO₂

: 1586023-59-7
ethyl 5-{isopropyl[(isopropyl carbamoyl)amino]methyl}-2-tertbutyl-3-phenylisoxazolidine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Inert atmosphere; Reflux

2: toluene / 24 h / 80 °C / Inert atmosphere

In toluene;
DOI:10.3184/174751913X13783169779948