N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

Base Information

Chemical Name:N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid
CAS No.:126937-41-5
Molecular Formula:C18H24N2O6
Molecular Weight:364.398
Hs Code.:2933599090
European Community (EC) Number:672-407-7
DSSTox Substance ID:DTXSID00373529
Mol file:126937-41-5.mol

Synonyms:126937-41-5;N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid;4-Boc-1-Cbz-2-piperazinecarboxylic acid;4-[(2-methylpropan-2-yl)oxycarbonyl]-1-phenylmethoxycarbonylpiperazine-2-carboxylic acid;1-((Benzyloxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid;1-(benzyloxycarbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid;1-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid;MFCD07369991;SCHEMBL375852;(R)-4-tert-Butoxycarbonyl-1-(benzyloxycarbonyl)piperazine-2-carboxylic acid;DTXSID00373529;1-benzyloxycarbonyl-4-tert-butoxycarbonyl-piperazine-2-carboxylic acid;MFCD01631192;piperazine-1,2,4-tricarboxylic acid 1-benzyl ester 4-tert-butyl ester;AKOS015841574;AB19897;AB32483;AC-6559;CS-W009779;AS-38503;SY035543;A2660;FT-0643059;FT-0687386;FT-0689643;BOC-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID;EN300-209139;Q-102276;N-4-Boc-N-1-cbz-2-piperazine carboxylic acid, AldrichCPR;1-(benzyloxycarbonyl)-4-(tert.butoxycarbonyl)-2-piperazinecarboxylic acid;1-benzyloxycarbonyl-4-(t-butoxycarbonyl)-piperazine-2-carboxylic acid;1-[(benzyl oxy)carbonyl]-4-(tert-butoxy carbonyl) piperazine-2-carboxylic acid;1-[(Benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)-piperazine-2-carboxylic acid;1-[(benzyloxy)carbonyl]-4-[(tert-butoxy)carbonyl]piperazine-2-carboxylic acid;N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID

Suppliers and Price of N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-4-Boc-N-1-Cbz-2-piperazineCarboxylicAcid
50mg
$ 45.00

Oakwood
N-4-Boc-N-1-Cbz-2-piperazinecarboxylicacid
1g
$ 160.00

Oakwood
N-4-Boc-N-1-Cbz-2-piperazinecarboxylicacid
250mg
$ 88.00

Crysdot
4-Boc-1-Cbz-2-piperazinecarboxylicacid 97%
1g
$ 74.00

Crysdot
4-Boc-1-Cbz-2-piperazinecarboxylicacid 97%
5g
$ 223.00

Chemenu
1-[(Benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)-piperazine-2-carboxylicacid 95%+
5g
$ 274.00

Biosynth Carbosynth
N-4-Boc-N-1-Cbz-2-piperazine carboxylicacid
500 mg
$ 55.00

Biosynth Carbosynth
N-4-Boc-N-1-Cbz-2-piperazine carboxylicacid
2 g
$ 162.00

Biosynth Carbosynth
N-4-Boc-N-1-Cbz-2-piperazine carboxylicacid
1 g
$ 93.00

Biosynth Carbosynth
N-4-Boc-N-1-Cbz-2-piperazine carboxylicacid
5 g
$ 324.00

Total 47 raw suppliers

Chemical Property of N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

Chemical Property:

Vapor Pressure:1.22E-11mmHg at 25°C
Melting Point:150-152 °C
Refractive Index:1.575
Boiling Point:518.9 °C at 760 mmHg
PKA:3.68±0.20(Predicted)
Flash Point:267.6 °C
PSA：96.38000
Density:1.272 g/cm³
LogP:2.20490
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:364.16343649
Heavy Atom Count:26
Complexity:524

Purity/Quality:

99%, ^*data from raw suppliers

N-4-Boc-N-1-Cbz-2-piperazineCarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCN(C(C1)C(=O)O)C(=O)OCC2=CC=CC=C2

Technology Process of N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

There total 11 articles about N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 128019-59-0
piperazine-1,3-dicarboxylic acid 1-tert-butyl ester

: 126937-41-5
1-(benzyloxycarbonyl)-4-(tert-butoxycarbonyl)-2-piperazinecarboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In water; acetone; at 0 - 20 ℃; for 5.5h; Inert atmosphere;

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 58632-95-4
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

: 3022-15-9,126330-90-3,133525-05-0,135841-26-8
piperazine-2-carboxylic acid dihydrochloride

: 126937-41-5
1-(benzyloxycarbonyl)-4-(tert-butoxycarbonyl)-2-piperazinecarboxylic acid

Guidance literature:: 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile; piperazine-2-carboxylic acid dihydrochloride; With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; pH=11;

N-(Benzyloxycarbonyloxy)succinimide; In 1,4-dioxane; water; at 0 - 20 ℃; pH=10;

With hydrogenchloride; In diethyl ether; water; pH=1;