6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine

Base Information

• Chemical Name: 6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine
• CAS No.: 1252554-39-4
• Molecular Formula: C₂₇H₂₃N₇O
• Molecular Weight: 461.526

Synonyms:6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine

Chemical Property of 6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine

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Technology Process of 6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine

There total 1 articles about 6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N₄-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloro-N4-[1-(phenylmethyl)cyclopropyl]-2,4-pyrimidinediamine (1227910-85-1) + 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[2,3][1,4]oxazepino[5,6,7-cd]indazol-2(11H)-yl)ethan-1-one (1252554-82-7) → 6-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-N4-[1-(phenyl methyl)cyclopropyl]-2,4-pyrimidinediamine (1252554-39-4)

Guidance literature:

With potassium phosphate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; water; at 140 ℃; for 1h; Sealed tube; Irradiation with microwave;

upstream raw materials:

6-chloro-N₄-[1-(phenylmethyl)cyclopropyl]-2,4-pyrimidinediamine

1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[2,3][1,4]oxazepino[5,6,7-cd]indazol-2(11H)-yl)ethan-1-one

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